Suppr超能文献

[保守性切除术后新的同侧肿瘤定位行再次肺切除的结果]

[Results of repeated pulmonary resection in new homolateral neoplastic localization after conservative resection].

作者信息

Massard G, Lyons G, Roeslin N, Kessler R, Hentz J G, Dumont P, Wihlm J M, Morand G

机构信息

Service de Chirurgie Thoracique, Hôpital Civil, Strasbourg.

出版信息

Ann Chir. 1995;49(9):835-40.

PMID:8554282
Abstract

From 1978 through 1992, 93 patients with a previous lobectomy for bronchogenic cancer were referred for homolateral cancer recurrence. Forty-six patients were contraindicated for carcinologic reasons (30 stage IIIb and 16 stage IV). Forty-seven patients (50.5%) were resectable, but 17 did not undergo surgery for associated medical problems (n = 11) or refusal (n = 6). The remaining 30 patients form the population of the present study: 29 males and 1 female; mean age of 61 years (range 47-72). The previous cancer was stage I in 26 and stage II in 4. The mean interval between the 2 cancer diagnoses was 30 months (range 6-97). Three patients underwent an exploratory thoracotomy (10%): 2 had mediastinal involvement and 1 had pleural metastases. Twenty-two (73%) underwent a completion pneumonectomy, and 5 had miscellaneous conservative resections. There were 4 operative deaths (13%): one intraoperative bleeding, 1 postoperative bleeding, 1 pulmonary embolism, 1 pneumonia. Four patients had nonfatal surgical complications: 2 clottings (reexploration), 1 empyema (lavage) and 1 bronchopleural fistula (thoracoplasty). Resected patients were staged as follows: 13 stage I, 4 stage II, 10 stage III. Survival following resection including operative mortality at 3 an 5 years was estimated as 52.5% and 44% for the whole series (72% for stage I). We conclude that repeat surgery conveys an increased risk, but may achieve valuable long-term results.

摘要

1978年至1992年期间,93例曾因支气管源性癌接受肺叶切除术的患者因同侧癌症复发前来就诊。46例患者因肿瘤学原因被列为手术禁忌(30例为Ⅲb期,16例为Ⅳ期)。47例患者(50.5%)可切除,但17例因合并内科问题(n = 11)或拒绝手术(n = 6)未接受手术。其余30例患者构成了本研究的对象:29例男性,1例女性;平均年龄61岁(范围47 - 72岁)。既往癌症为Ⅰ期的有26例,Ⅱ期的有4例。两次癌症诊断之间的平均间隔时间为30个月(范围6 - 97个月)。3例患者接受了开胸探查术(10%):2例有纵隔受累,1例有胸膜转移。22例(73%)接受了全肺切除术,5例进行了其他保守性切除术。有4例手术死亡(13%):1例术中出血,1例术后出血,1例肺栓塞,1例肺炎。4例患者出现非致命性手术并发症:2例凝血(再次探查),1例脓胸(灌洗),1例支气管胸膜瘘(胸廓成形术)。切除术后患者的分期如下:Ⅰ期13例,Ⅱ期4例,Ⅲ期10例。整个系列切除术后包括手术死亡率在内的3年和5年生存率估计分别为52.5%和44%(Ⅰ期为72%)。我们得出结论,再次手术风险增加,但可能取得有价值的长期效果。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验