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新生儿淋巴细胞产生白细胞迁移抑制因子。

Production of leucocyte migration inhibitory factor by neonatal lymphocytes.

作者信息

Wolf R L, Lomnitzer R, Rabson A R

出版信息

S Afr Med J. 1976 Jun 19;50(26):992-3.

PMID:781870
Abstract

Lymphocytes (mononuclear cells) from cord blood of 10 normal placentas and from 10 normal adults were assessed for production of leucocyte migration inhibiting factor (LIF) after phytohaemagglutinin (PHA) stimulation, as a measure of cell-mediated immunity. Mononuclear cells from both adult and cord blood produced adequate quantities of LIF, indicating that neonatal lymphocytes have the ability to manufacture normal amounts of lymphokines.

摘要

对来自10例正常胎盘脐带血和10名正常成年人的淋巴细胞(单核细胞)进行评估,检测其在植物血凝素(PHA)刺激后白细胞迁移抑制因子(LIF)的产生情况,以此作为细胞介导免疫的一项指标。来自成人和脐带血的单核细胞均产生了足够量的LIF,这表明新生儿淋巴细胞有能力产生正常量的淋巴因子。

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