Hecher K, Sullivan I D, Nicolaides K H
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London.
Br Heart J. 1994 Nov;72(5):457-60. doi: 10.1136/hrt.72.5.457.
This report describes the sequence of events in the development and subsequent spontaneous resolution of functional tricuspid valve atresia in the donor fetus in a case of twin to twin transfusion syndrome. Fetoscopic laser coagulation of the placental anastomoses was performed at 20 weeks' gestation. Subsequently, there was evidence of increased placental vascular resistance in the donor twin and major impairment of right ventricular function with no forward flow through the tricuspid valve. During the next four weeks, however, there was spontaneous and complete recovery of ventricular function and resolution of the functional tricuspid valve atresia. These findings suggest that alterations in fetal haemodynamics may result in structural cardiac abnormality and may be the precursors of some forms of congenital heart disease.
本报告描述了一例双胎输血综合征中供体胎儿功能性三尖瓣闭锁的发生及随后自发缓解的一系列事件。在妊娠20周时对胎盘吻合口进行了胎儿镜激光凝固术。随后，有证据表明供体双胎的胎盘血管阻力增加，右心室功能严重受损，三尖瓣无前向血流。然而，在接下来的四周内，心室功能自发且完全恢复，功能性三尖瓣闭锁得到缓解。这些发现表明，胎儿血流动力学的改变可能导致心脏结构异常，并且可能是某些形式先天性心脏病的先兆。
