McKenney D W, Siegel N J
Division of Pediatric Nephrology, Yale University School of Medicine, New Haven, CT 06520-8064.
Pediatr Nephrol. 1994 Oct;8(5):587-8. doi: 10.1007/BF00858134.
Cutaneous manifestations occur in a significant number of patients with Wegener's granulomatosis (WG); however, the presentation and histopathology of these lesions are highly variable and may present problems in diagnosis. We report the presentation of a single large skin lesion in a pediatric patient with a history of WG and the characterization of this lesion by magnetic resonance imaging (MRI) and histopathology. MRI was helpful in delineating the extent of the lesion, although a skin biopsy was necessary to confirm the diagnosis of the vasculitic nature of the lesion.
相当数量的韦格纳肉芽肿(WG)患者会出现皮肤表现;然而,这些病变的表现和组织病理学变化很大,可能会在诊断上带来问题。我们报告了一名有WG病史的儿科患者出现单个大的皮肤病变,并通过磁共振成像(MRI)和组织病理学对该病变进行了特征描述。MRI有助于确定病变范围,不过需要进行皮肤活检以确诊病变的血管炎性本质。