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新诊断霍奇金淋巴瘤的骨髓检查:英国的当前实践

Bone marrow examination in newly diagnosed Hodgkin's disease: current practice in the United Kingdom.

作者信息

Howard M R, Taylor P R, Lucraft H H, Taylor M J, Proctor S J

机构信息

Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

出版信息

Br J Cancer. 1995 Jan;71(1):210-2. doi: 10.1038/bjc.1995.43.

DOI:10.1038/bjc.1995.43
PMID:7819042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2033458/
Abstract

In the UK Hodgkin's disease is usually treated by either clinical oncologists or haematologists. A national study of the performance of bone marrow examination in newly diagnosed Hodgkin's disease was undertaken to establish current practice. A total of 620 questionnaires were despatched, and replies were received from 60% of consultants (45% of clinical oncologists and 70% of haematologists). Bone marrow examination was performed in all new cases significantly more often by haematologists than by clinical oncologists (74% vs 40%, P < 0.001). Among haematologists, there was no correlation between the number of new patients seen annually and practice, however clinical oncologists were even less likely to perform routine bone marrow biopsies if they saw more than ten patients per year (P < 0.02). Where bone marrow examination was performed selectively, the most common criteria used were peripheral blood cytopenia and advanced-stage disease. These criteria were applied in the same way by both clinical oncologists and haematologists. Bone marrow biopsy, an invasive and often painful procedure, is currently performed more frequently in Hodgkin's disease than can be recommended on the basis of recent studies in the literature and associated guidelines. There is a significant difference in practice between clinical oncologists and haematologists, and this raises the wider issue of the influence of hospital specialisation on patient management.

摘要

在英国,霍奇金淋巴瘤通常由临床肿瘤学家或血液学家进行治疗。开展了一项关于新诊断的霍奇金淋巴瘤骨髓检查情况的全国性研究,以确定当前的治疗实践。共发放了620份问卷,收到了60%的顾问(45%的临床肿瘤学家和70%的血液学家)的回复。血液学家对所有新病例进行骨髓检查的比例显著高于临床肿瘤学家(74%对40%,P<0.001)。在血液学家中,每年诊治的新患者数量与检查实践之间没有相关性,然而,如果临床肿瘤学家每年诊治超过10名患者,他们进行常规骨髓活检的可能性更低(P<0.02)。在进行选择性骨髓检查时,最常用的标准是外周血细胞减少和疾病晚期。临床肿瘤学家和血液学家应用这些标准的方式相同。骨髓活检是一种侵入性且通常会带来疼痛的操作,目前在霍奇金淋巴瘤中的执行频率高于近期文献研究和相关指南所建议的频率。临床肿瘤学家和血液学家在实践中存在显著差异,这引发了关于医院专科化对患者管理影响的更广泛问题。

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本文引用的文献

1
Staging and follow up of patients with lymphoproliferative disorder.淋巴增生性疾病患者的分期及随访
J Clin Pathol. 1993 Mar;46(3):286. doi: 10.1136/jcp.46.3.286-a.
2
Hormonal protection from procarbazine-induced testicular damage is selective for survival and recovery of stem spermatogonia.激素对丙卡巴肼诱导的睾丸损伤的保护作用对精原干细胞的存活和恢复具有选择性。
Cancer Res. 1994 Feb 15;54(4):1027-34.
3
Protection by gonadal steroid hormones against procarbazine-induced damage to spermatogenic function in LBNF1 hybrid rats.性腺甾体激素对LBNF1杂交大鼠中丙卡巴肼诱导的生精功能损伤的保护作用。
J Androl. 1993 Jul-Aug;14(4):257-66.
4
Assessment of bone marrow histology in Hodgkin's disease: correlation with clinical factors.霍奇金淋巴瘤骨髓组织学评估:与临床因素的相关性
Br J Haematol. 1982 Jul;51(3):345-60. doi: 10.1111/j.1365-2141.1982.tb02790.x.
5
The effects of Hodgkin's disease and combination chemotherapy on gonadal function in the adult male.霍奇金病及联合化疗对成年男性性腺功能的影响。
Cancer. 1982 Feb 1;49(3):418-22. doi: 10.1002/1097-0142(19820201)49:3<418::aid-cncr2820490304>3.0.co;2-a.
6
Gonadal dysfunction in patients receiving chemotherapy for cancer.接受癌症化疗患者的性腺功能障碍
Ann Intern Med. 1980 Jul;93(1):109-14. doi: 10.7326/0003-4819-93-1-109.
7
Fertility after chemotherapy for testicular cancer.睾丸癌化疗后的生育能力。
J Clin Oncol. 1983 Mar;1(3):179-83. doi: 10.1200/JCO.1983.1.3.179.
8
Protection from cyclophosphamide-induced testicular damage with an analogue of gonadotropin-releasing hormone.使用促性腺激素释放激素类似物预防环磷酰胺诱导的睾丸损伤。
Lancet. 1981 May 23;1(8230):1132-4. doi: 10.1016/s0140-6736(81)92301-1.
9
Clomiphene citrate: a correlation of its effect on sperm concentration and morphology, total gonadotropins, ICSH, estrogen and testosterone excretion, and testicular cytology in normal men.枸橼酸氯米芬:其对正常男性精子浓度和形态、总促性腺激素、促间质细胞激素、雌激素和睾酮排泄以及睾丸细胞学影响的相关性
J Clin Endocrinol Metab. 1969 May;29(5):638-49. doi: 10.1210/jcem-29-5-638.
10
Effect of clomiphene on testicular protein synthesis in vitro.克罗米芬对体外睾丸蛋白质合成的影响。
Biochem Pharmacol. 1970 Oct;19(10):2701-5. doi: 10.1016/0006-2952(70)90096-1.