Suppr超能文献

新诊断霍奇金淋巴瘤的骨髓检查:英国的当前实践

Bone marrow examination in newly diagnosed Hodgkin's disease: current practice in the United Kingdom.

作者信息

Howard M R, Taylor P R, Lucraft H H, Taylor M J, Proctor S J

机构信息

Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

出版信息

Br J Cancer. 1995 Jan;71(1):210-2. doi: 10.1038/bjc.1995.43.

Abstract

In the UK Hodgkin's disease is usually treated by either clinical oncologists or haematologists. A national study of the performance of bone marrow examination in newly diagnosed Hodgkin's disease was undertaken to establish current practice. A total of 620 questionnaires were despatched, and replies were received from 60% of consultants (45% of clinical oncologists and 70% of haematologists). Bone marrow examination was performed in all new cases significantly more often by haematologists than by clinical oncologists (74% vs 40%, P < 0.001). Among haematologists, there was no correlation between the number of new patients seen annually and practice, however clinical oncologists were even less likely to perform routine bone marrow biopsies if they saw more than ten patients per year (P < 0.02). Where bone marrow examination was performed selectively, the most common criteria used were peripheral blood cytopenia and advanced-stage disease. These criteria were applied in the same way by both clinical oncologists and haematologists. Bone marrow biopsy, an invasive and often painful procedure, is currently performed more frequently in Hodgkin's disease than can be recommended on the basis of recent studies in the literature and associated guidelines. There is a significant difference in practice between clinical oncologists and haematologists, and this raises the wider issue of the influence of hospital specialisation on patient management.

摘要

在英国,霍奇金淋巴瘤通常由临床肿瘤学家或血液学家进行治疗。开展了一项关于新诊断的霍奇金淋巴瘤骨髓检查情况的全国性研究,以确定当前的治疗实践。共发放了620份问卷,收到了60%的顾问(45%的临床肿瘤学家和70%的血液学家)的回复。血液学家对所有新病例进行骨髓检查的比例显著高于临床肿瘤学家(74%对40%,P<0.001)。在血液学家中,每年诊治的新患者数量与检查实践之间没有相关性,然而,如果临床肿瘤学家每年诊治超过10名患者,他们进行常规骨髓活检的可能性更低(P<0.02)。在进行选择性骨髓检查时,最常用的标准是外周血细胞减少和疾病晚期。临床肿瘤学家和血液学家应用这些标准的方式相同。骨髓活检是一种侵入性且通常会带来疼痛的操作,目前在霍奇金淋巴瘤中的执行频率高于近期文献研究和相关指南所建议的频率。临床肿瘤学家和血液学家在实践中存在显著差异,这引发了关于医院专科化对患者管理影响的更广泛问题。

相似文献

3
The value of staging bone marrow trephine biopsy in Hodgkin's disease.
Eur J Haematol. 1987 Jul;39(1):66-70. doi: 10.1111/j.1600-0609.1987.tb00166.x.
5
Bone marrow biopsy in Hodgkin's lymphoma.霍奇金淋巴瘤的骨髓活检
Eur J Haematol. 2004 Sep;73(3):149-55. doi: 10.1111/j.1600-0609.2004.00292.x.
9
Phagocytic macrophages in the bone marrow biopsies of children with Hodgkin's disease.
Pediatr Pathol. 1986;6(4):369-75. doi: 10.3109/15513818609041550.

引用本文的文献

1
Bone involvement in patients with lymphoma: the role of FDG-PET/CT.淋巴瘤患者的骨受累:FDG-PET/CT的作用。
Eur J Nucl Med Mol Imaging. 2007 Jan;34(1):60-7. doi: 10.1007/s00259-006-0238-8. Epub 2006 Sep 22.

本文引用的文献

7
Fertility after chemotherapy for testicular cancer.睾丸癌化疗后的生育能力。
J Clin Oncol. 1983 Mar;1(3):179-83. doi: 10.1200/JCO.1983.1.3.179.
10

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验