Maguire H C
Department of Medicine, Thomas Jefferson University School of Medicine, Philadelphia, Pa.
Int Arch Allergy Immunol. 1995 Feb;106(2):166-8. doi: 10.1159/000236839.
Interleukin-12 (IL-12) is a heterodimeric cytokine that has pleiotropic effects on the immune response. We have studied the effect of recombinant IL-12 on allergic contact dermatitis in the mouse. IL-12 substantially up-regulates the induction of sensitivity to the contact allergens dinitrofluorobenzene and oxazolone.
白细胞介素-12(IL-12)是一种对免疫反应具有多效性作用的异二聚体细胞因子。我们研究了重组IL-12对小鼠过敏性接触性皮炎的影响。IL-12显著上调对接触性变应原二硝基氟苯和恶唑酮的敏感性诱导。