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胎儿水肿通常由血型抗体引起,在常规筛查中通常无法检测到。

Hydrops fetalis caused by a blood group antibody usually undetected in routine screening.

作者信息

Smoleniec J, Anderson N, Poole G

机构信息

St Michael's Hospital, Bristol.

出版信息

Arch Dis Child Fetal Neonatal Ed. 1994 Nov;71(3):F216-7. doi: 10.1136/fn.71.3.f216.

Abstract

A case of isoimmunisation in pregnancy caused by antibodies to the Kpa red blood cell antigen is described. The preceding pregnancy had resulted in fetal hydrops for which no cause was found as the antibody screening cells used to investigate the fetal hydrops were Kpa negative. This case emphasises the importance of serological screening at a reference laboratory for low frequency red cell antigens before a diagnosis of non-immune hydrops is made.

摘要

本文描述了一例由抗Kpa红细胞抗原抗体引起的孕期同种免疫病例。前次妊娠导致胎儿水肿,由于用于调查胎儿水肿的抗体筛查细胞为Kpa阴性,未发现病因。该病例强调了在诊断非免疫性水肿之前,在参考实验室对低频红细胞抗原进行血清学筛查的重要性。

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本文引用的文献

1
Investigation of nonimmune hydrops fetalis.非免疫性胎儿水肿的研究。
Am J Obstet Gynecol. 1984 Dec 1;150(7):805-12. doi: 10.1016/0002-9378(84)90453-8.
3
Treatment options for the fetus with alloimmune hemolytic disease.
Transfus Med Rev. 1990 Jul;4(3):191-207. doi: 10.1016/s0887-7963(90)70265-9.

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