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股骨头缺血性坏死:当前概念与争议

Osteonecrosis of the femoral head: current concepts and controversies.

作者信息

Mulliken B D

机构信息

University of Iowa Hospitals and Clinics, Dept. of Orthopaedic Surgery, Iowa City 52242.

出版信息

Iowa Orthop J. 1993;13:160-6.

Abstract

Despite many investigations into ON of the femoral head, many issues remain unresolved. The pathogenesis in most cases is only speculative and may involve intravascular factors such as microemboli or extravascular factors such as increased interosseous pressure. MRI has emerged as the diagnostic test of choice for suspected early lesions, and radiographs should be used to diagnose and follow advanced lesions. Bone scanning can be useful for early diagnosis and CT scanning or tomography may help plan surgical procedures. The role of the functional exploration of bone is controversial. The natural history of early lesions is unknown; this makes it difficult to evaluate results of treatment. Radiographic ON will usually progress to collapse and arthrosis if treated nonoperatively. The role of core decompression or other joint preserving operations to prevent collapse is controversial, since the reports of success and complication rates have been extremely variable. These procedures are ineffective if used after radiographic collapse. Total hip replacement is the only satisfactory treatment for advanced symptomatic stages, but is relatively contraindicated in young active patients. Further research is needed to assess the natural history of early ON and evaluate the role of surgery in preventing progression.

摘要

尽管对股骨头缺血性坏死进行了诸多研究,但许多问题仍未得到解决。大多数情况下,其发病机制仅为推测,可能涉及血管内因素如微栓子,或血管外因素如骨内压升高。磁共振成像(MRI)已成为疑似早期病变的首选诊断检查方法,而X线片应用于诊断和随访晚期病变。骨扫描对早期诊断可能有用,计算机断层扫描(CT)或体层摄影术可能有助于手术方案的制定。骨功能探查的作用存在争议。早期病变的自然病程尚不清楚,这使得评估治疗结果变得困难。如果不进行手术治疗,X线片显示的缺血性坏死通常会发展为塌陷和关节病。核心减压或其他保留关节手术预防塌陷的作用存在争议,因为成功和并发症发生率的报道差异极大。如果在X线片显示塌陷后采用这些手术则无效。全髋关节置换术是晚期有症状阶段唯一令人满意的治疗方法,但在年轻活跃患者中相对禁忌。需要进一步研究来评估早期缺血性坏死的自然病程,并评估手术在预防病情进展中的作用。

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