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通过消耗试验和免疫荧光法对未筛选血清中抗核抗体测定结果的比较。

Comparison of antinuclear antibody determinations in unselected sera by consumption test and immunofluorescence.

作者信息

Weheba A S

出版信息

Z Rheumatol. 1976 May-Jun;35(5-6):210-6.

PMID:782080
Abstract

The correlation of the determination of antinuclear antibodies, as shown by consumption tests and immunofluorescence was investigated in a collective of 100 sera of patients suspected for SLE, collagenosis and rheumatoid arthritis, sent for routine screening investigation. The results of both methods correlated in 78% of sera, both results being either positive or negative. No correlation was observed in 22% of sera, one test being positive, the other negative. Statistical evaluation by the X2 test showed that both techniques did not differ statistically in their results. A correlation coefficient r=0,45 indicated furthermore that the results of both techniques correlated significantly. The percentage of positive results obtained with these and other methods is discussed.

摘要

在一批因疑似系统性红斑狼疮、胶原病和类风湿性关节炎而送检进行常规筛查的100份患者血清样本中,对通过消耗试验和免疫荧光法检测抗核抗体的相关性进行了研究。两种方法的结果在78%的血清样本中呈现相关性,即两种结果均为阳性或均为阴性。在22%的血清样本中未观察到相关性,一种检测呈阳性,另一种呈阴性。通过卡方检验进行的统计学评估表明,两种技术的结果在统计学上无差异。此外,相关系数r = 0.45表明两种技术的结果具有显著相关性。文中还讨论了使用这些方法及其他方法获得的阳性结果百分比。

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