Onaka U, Nagao T, Ibayashi S, Sadoshima S, Fujishima M
Second Department of Internal Medicine, Faculty of Medicine, Kyushyu University.
Rinsho Shinkeigaku. 1994 Sep;34(9):930-2.
A case of acute idiopathic pandysautonomia (AIPD) complicated with acute pancreatitis and liver injury was reported. A 43-year-old woman acutely developed abdominal pain, low grade fever, lymphoadenopathy and generalized erythema in May 1992. She was found to have autonomic dysfunctions, such as orthostatic hypotension, hypohidrosis, paralytic ileus and urinary retention. A systematic investigation of autonomic function revealed an impairment of both sympathetic and parasympathetic post-ganglionic nerves. Serum concentrations of amylase, lipase, elastase 1, and transaminase and amylase creatinine clearance ratio were elevated in the early stage of the disease. No significant serological findings for viral infections were detected to suggest any special etiology of the disease; the symptoms gradually improved, although incompletely, after several months from the onset. AIPD complicated with acute pancreatitis or liver injury is uncommon. A possible link between undetectable viral infection and AIPD was discussed.
报告了一例急性特发性全自主神经功能不全（AIPD）合并急性胰腺炎和肝损伤的病例。一名43岁女性于1992年5月急性出现腹痛、低热、淋巴结病和全身红斑。她被发现存在自主神经功能障碍，如直立性低血压、少汗、麻痹性肠梗阻和尿潴留。对自主神经功能的系统检查显示交感和副交感神经节后神经均受损。疾病早期血清淀粉酶、脂肪酶、弹性蛋白酶1、转氨酶以及淀粉酶肌酐清除率升高。未检测到病毒感染的显著血清学结果以提示该疾病的任何特殊病因；发病数月后症状逐渐改善，尽管并不完全。AIPD合并急性胰腺炎或肝损伤并不常见。讨论了无法检测到的病毒感染与AIPD之间可能的联系。
