Horton R C, Gosling P, Reeves C N, Payne M, Nagle R E
Cardiology Department, Selly Oak Hospital, Birmingham, U.K.
Eur Heart J. 1994 Oct;15(10):1353-5. doi: 10.1093/oxfordjournals.eurheartj.a060393.
Thirty-three subjects underwent exercise electrocardiogram testing, 20 had a history of myocardial infarction and 13 were age-matched volunteers. Exercise electrocardiograms were positive in 15 subjects, negative in 12 and anomalous in six. Urinary microalbumin excretion was measured at rest, 30 and 60 min after exercise. Urinary microalbumin excretion was expressed as the albumin-creatinine ratio in mg.mmol-1. In the positive exercise electrocardiogram group median albumin-creatinine ratio increased from 1.0 mg.mmol-1 (95% CI 0.94-1.49) at rest to 2.0 mg.mmol-1 (95% CI 1.51-3.94) 30 min after exercise, whilst in the negative electrocardiogram group median resting and 30 min post exercise albumin-creatinine ratio values of 0.85 (95% CI 0.53-1.32) and 1.80 (95% CI 0.63-2.32) mg.mmol-1 respectively were not significantly different. These results suggest that exercise-induced myocardial ischaemia is associated with increased urinary microalbumin excretion.
33名受试者接受了运动心电图测试，其中20人有心肌梗死病史，13人是年龄匹配的志愿者。运动心电图结果为阳性的有15名受试者，阴性的有12名，异常的有6名。在静息状态、运动后30分钟和60分钟测量尿微量白蛋白排泄量。尿微量白蛋白排泄量以白蛋白-肌酐比值（mg.mmol-1）表示。在运动心电图阳性组中，白蛋白-肌酐比值中位数从静息时的1.0 mg.mmol-1（95%CI 0.94-1.49）增加到运动后30分钟的2.0 mg.mmol-1（95%CI 1.51-3.94），而在心电图阴性组中，静息时和运动后30分钟白蛋白-肌酐比值中位数分别为0.85（95%CI 0.53-1.32）和1.80（95%CI 0.63-2.32）mg.mmol-1，差异无统计学意义。这些结果表明，运动诱发的心肌缺血与尿微量白蛋白排泄增加有关。
