Péterfy M, Gyuris T, Basu R, Takács L
Amgen Inc., Thousand Oaks, CA 91320.
Gene. 1994 Dec 15;150(2):415-6. doi: 10.1016/0378-1119(94)90468-5.
The nucleotide (nt) sequence of the LIS-1 cDNA encoding the murine lissencephaly-1 (LIS-1) protein has been determined. The deduced protein shows a very high degree (99.8%) of homology with human LIS-1, having a single conservative amino acid (aa) change out of 410 aa and is identical to a subunit of bovine platelet-activating factor (PAF) acetylhydrolase.
编码小鼠无脑回畸形蛋白-1(LIS-1)的LIS-1互补DNA(cDNA)的核苷酸(nt)序列已被确定。推导的蛋白质与人类LIS-1显示出非常高的同源性(99.8%),在410个氨基酸中有一个保守氨基酸(aa)变化,并且与牛血小板活化因子(PAF)乙酰水解酶的一个亚基相同。