Elhage A, Delest A, Tordjman N, Carpentier F, Querleu D
Clinique Universitaire de Gynécologie, d'Obstétrique et de Pathologie de la Reproduction, Pavillon Paul-Gelle, Roubaix.
J Gynecol Obstet Biol Reprod (Paris). 1994;23(7):762-6.
The goal of our study was to evaluate peritoneal and retroperitoneal healing and therefore to assess the optimal date for surgery after laparoscopic lymphadenectomy. A para-aortic lymphadenectomy was carried out in 5 groups of 5 New Zealand female rabbits. The perivascular cicatricial tissue was dissected after specific delay for each group (48 hours, 1 week, 2 weeks, 4 weeks, and 6 weeks). Peritoneal reconstruction was observed in 80% of the "48 h" group, and in 100% in the other groups (from 1 to 6 weeks). Vascular injury complicated dissection in 40% for the "1 week" group, in 80% for the "2 weeks" group, and in 20% for the "6 weeks" group. No vascular complication was observed in the "48 h" and "4 weeks" groups. The results of "1 week" and "2 weeks" were combined. The results of the "4 weeks" group were compared, with the Fisher test, to the results of a "1 week" and "2 weeks" combined group as well as to the results of the "six weeks" group. Four weeks seem to be the optimal date for a possible surgical excision after a laparoscopic lymphadenectomy.
我们研究的目的是评估腹膜和腹膜后愈合情况，从而确定腹腔镜淋巴结清扫术后的最佳手术日期。对5组，每组5只新西兰雌性家兔进行腹主动脉旁淋巴结清扫术。每组在特定延迟时间（48小时、1周、2周、4周和6周）后解剖血管周围瘢痕组织。“48小时”组80%观察到腹膜重建，其他组（1至6周）100%观察到腹膜重建。“1周”组40%、“2周”组80%、“6周”组20%的血管损伤使解剖过程复杂化。“48小时”组和“4周”组未观察到血管并发症。将“1周”组和“2周”组的结果合并。采用Fisher检验，将“4周”组的结果与“1周”和“2周”合并组的结果以及“6周”组的结果进行比较。四周似乎是腹腔镜淋巴结清扫术后进行手术切除的最佳日期。
