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[老年人非Q波心肌梗死的临床特征及长期预后:与Q波心肌梗死的比较]

[Clinical features and long-term outcome of non-Q wave myocardial infarction in the elderly: comparison with Q wave myocardial infarction].

作者信息

Kishi K, Hiasa Y, Kinoshita M, Kondoh N, Fujinaga H, Ohtani R, Wada T, Aihara T

机构信息

Division of Cardiology, Komatsushima Red Cross Hospital, Tokushima.

出版信息

J Cardiol. 1994 Nov-Dec;24(6):433-7.

PMID:7823281
Abstract

The clinical features and long-term outcome of non-Q wave myocardial infarction (NQMI) in the elderly were assessed in 24 patients with NQMI and compared with those in 48 patients with Q wave myocardial infarction (QMI). NQMI patients had a significantly lower maximal peak of serum creatine phosphokinase activity and lower incidence of pump failure during the acute phase. In-hospital mortality did not differ significantly between the NQMI and QMI patients. Evaluation of acute-phase coronary angiographic features within 6 hours of onset found a significantly higher incidence of infarct-related vessels in the NQMI patients, but the frequency of multivessel disease and the level of collateral flow did not differ between the two groups. Fifteen of the 24 NQMI patients and 34 of the 48 QMI patients underwent emergency coronary revascularization procedures of percutaneous transluminal coronary angioplasty (PTCA) or intracoronary thrombolysis. Successful recanalization was more frequent and the time to recanalization was shorter in the NQMI patients. The requirement for coronary revascularization (PTCA or coronary artery bypass graft) in the chronic phase for residual stenosis did not differ significantly between the two groups. Left ventricular ejection fractions were significantly better in the NQMI patients. The short- and long-term outcomes in elderly patients with NQMI and QMI were good and did not differ between the two groups, probably reflecting the active performance of revascularization in the acute and chronic phases.

摘要

对24例非Q波心肌梗死(NQMI)老年患者的临床特征和长期预后进行了评估,并与48例Q波心肌梗死(QMI)患者进行了比较。NQMI患者急性期血清肌酸磷酸激酶活性的最大峰值显著较低,泵衰竭发生率也较低。NQMI和QMI患者的院内死亡率无显著差异。发病6小时内对急性期冠状动脉造影特征的评估发现,NQMI患者梗死相关血管的发生率显著较高,但两组多支血管病变的频率和侧支血流水平无差异。24例NQMI患者中的15例和48例QMI患者中的34例接受了经皮腔内冠状动脉成形术(PTCA)或冠状动脉内溶栓等急诊冠状动脉血运重建术。NQMI患者成功再通更为频繁,再通时间更短。两组慢性期因残余狭窄而行冠状动脉血运重建(PTCA或冠状动脉旁路移植术)的需求无显著差异。NQMI患者的左心室射血分数明显更好。老年NQMI和QMI患者的短期和长期预后良好,两组之间无差异,这可能反映了急性期和慢性期血运重建的积极实施情况。

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