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日本阵发性室上性心动过速的射频导管消融术与药物治疗的成本效益

Cost effectiveness of radiofrequency catheter ablation versus medical treatment for paroxysmal supraventricular tachycardia in Japan.

作者信息

Ikeda T, Sugi K, Enjoji Y, Kasao M, Abe R, Ninomiya K, Yabuki S, Yamaguchi T

机构信息

Third Department of Internal Medicine, Ohashi Hospital, Toho University School of Medicine, Tokyo.

出版信息

J Cardiol. 1994 Nov-Dec;24(6):461-8.

PMID:7823285
Abstract

This study evaluated the cost of performing radiofrequency catheter ablation in Japanese patients with paroxysmal supraventricular tachycardia refractory to antiarrhythmic drug therapy in comparison with the cost of continuing pharmacologic treatment. Twenty patients (mean age 44 +/- 14 years) underwent successful ablation: 15 patients with Wolff-Parkinson-White syndrome and five with atrioventricular nodal reentrant tachycardia. The mean duration of symptoms was 77 +/- 60 months. The patients had been treated with 2.6 +/- 1.7 antiarrhythmic drugs before undergoing ablation. Charges derived from hospital bills were compared with the outpatient charges for the year before ablation. The mean hospital stay for the ablation procedure was 4.3 +/- 0.5 days. The mean total charge for ablation was 982,806 yen +/- 103,195, and 5.7 +/- 0.7 times the outpatient charges in the previous year. The majority of radical cure charges were the costs of the electrode catheters used in the ablation procedure. All patients had a successful outcome and required no additional antiarrhythmic drug therapy. If medical treatment were continued without ablation, the mean total life-expectancy charges were estimated at 7,064,726 yen +/- 3,116,621, 41.0 +/- 19.2 times the outpatient charges. The total life charges of medical treatment were significantly more than the total ablation charges (p < 0.001). This study suggests that radiofrequency catheter ablation is of clinical benefit in treating paroxysmal supraventricular tachycardia, and markedly reduces the cost of definitive therapy. This strategy appears to be more economical than pharmacologic treatment.

摘要

本研究评估了日本阵发性室上性心动过速且抗心律失常药物治疗无效的患者进行射频导管消融术的成本,并与继续药物治疗的成本进行比较。20例患者(平均年龄44±14岁)成功接受了消融术:15例为预激综合征患者,5例为房室结折返性心动过速患者。症状的平均持续时间为77±60个月。患者在接受消融术前曾使用2.6±1.7种抗心律失常药物进行治疗。将医院账单产生的费用与消融术前一年的门诊费用进行比较。消融手术的平均住院时间为4.3±0.5天。消融的平均总费用为982,806日元±103,195,是上一年门诊费用的5.7±0.7倍。大部分根治费用是消融手术中使用的电极导管的成本。所有患者均取得成功,无需额外的抗心律失常药物治疗。如果不进行消融而继续药物治疗,预计平均总预期寿命费用为7,064,726日元±3,116,621,是门诊费用的41.0±19.2倍。药物治疗的总寿命费用显著高于消融总费用(p<0.001)。本研究表明,射频导管消融术在治疗阵发性室上性心动过速方面具有临床益处,并显著降低了确定性治疗的成本。该策略似乎比药物治疗更经济。

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