Crespo D, Villegas J, Fernández-Viadero C, Ovejero V, Amodia J, Verduga R
Department of Anatomy and Cell Biology, Faculty of Medicine, University of Cantabria, Santander, Spain.
Mech Ageing Dev. 1994 Aug;75(2):131-40. doi: 10.1016/0047-6374(94)90081-7.
In 2-year-old mice, astrocytes of the supraoptic nucleus (SON) of the hypothalamus, placed in close contact with the meningeal covering contained concentric arrangements of cisterns in their cytoplasm called glial concentric bodies (GCBs). They are formed by a variable number of flattened cisterns without pores, and no anastomosis was observed between adjacent cisterns. Rough endoplasmic reticulum (RER) cisterns do not show continuity with fully developed GCBs, although a close continuity between RER cisterns and GCBs was present in images suggesting GCB formation. Concomitantly with the appearance of GCBs, ventral neurosecretory neurons of the SON showed a cytoplasmic membrane reinforced by the apposition of glial prolongations. The possible origin and function of these GCBs and lamellae are discussed here.
在2岁小鼠中，下丘脑视上核（SON）的星形胶质细胞与脑膜覆盖物紧密接触，其细胞质中含有称为胶质同心体（GCBs）的同心排列的池。它们由数量不等的无孔扁平池形成，相邻池之间未观察到吻合。粗面内质网（RER）池与完全发育的GCBs没有连续性，尽管在提示GCB形成的图像中RER池与GCBs之间存在紧密连续性。与GCBs出现同时，SON的腹侧神经分泌神经元的细胞质膜因胶质突起的附着而得到加强。本文讨论了这些GCBs和薄片的可能起源及功能。
