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High-frequency gene conversion between repeated C mu sequences integrated at the chromosomal immunoglobulin mu locus in mouse hybridoma cells.整合于小鼠杂交瘤细胞染色体免疫球蛋白μ位点的重复Cμ序列之间的高频基因转换。
Mol Cell Biol. 1995 Feb;15(2):766-71. doi: 10.1128/MCB.15.2.766.
2
Ectopic recombination within homologous immunoglobulin mu gene constant regions in a mouse hybridoma cell line.
Mol Cell Biol. 1992 Oct;12(10):4422-32. doi: 10.1128/mcb.12.10.4422-4432.1992.
3
High-frequency homologous recombination between duplicate chromosomal immunoglobulin mu heavy-chain constant regions.重复染色体免疫球蛋白μ重链恒定区之间的高频同源重组。
Mol Cell Biol. 1989 Dec;9(12):5500-7. doi: 10.1128/mcb.9.12.5500-5507.1989.
4
Cis-acting regulatory sequences promote high-frequency gene conversion between repeated sequences in mammalian cells.顺式作用调控序列促进哺乳动物细胞中重复序列之间的高频基因转换。
Nucleic Acids Res. 2004 Nov 4;32(19):5916-27. doi: 10.1093/nar/gkh926. Print 2004.
5
Nonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion.小鼠JH-Cδ基因座内位点的非同源重组伴随着Cμ缺失并转换为免疫球蛋白D分泌。
Mol Cell Biol. 1991 Nov;11(11):5660-70. doi: 10.1128/mcb.11.11.5660-5670.1991.
6
Analysis of mutations introduced into the chromosomal immunoglobulin mu gene.对引入染色体免疫球蛋白μ基因的突变的分析。
Somat Cell Mol Genet. 1993 Jul;19(4):299-311. doi: 10.1007/BF01232743.
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The mechanism of mammalian gene replacement is consistent with the formation of long regions of heteroduplex DNA associated with two crossing-over events.哺乳动物基因置换的机制与由两个交叉事件所关联的异源双链DNA长区域的形成是一致的。
Mol Cell Biol. 2001 Jan;21(2):501-10. doi: 10.1128/MCB.21.2.501-510.2001.
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The molecular basis of multiple vector insertion by gene targeting in mammalian cells.哺乳动物细胞中通过基因打靶实现多载体插入的分子基础。
Genetics. 1999 Mar;151(3):1143-55. doi: 10.1093/genetics/151.3.1143.
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Evidence for the murine IgH mu locus acting as a hot spot for intrachromosomal homologous recombination.小鼠免疫球蛋白重链μ基因座作为染色体内同源重组热点的证据。
J Immunol. 2002 Mar 1;168(5):2332-9. doi: 10.4049/jimmunol.168.5.2332.
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Mechanisms of double-strand-break repair during gene targeting in mammalian cells.哺乳动物细胞基因靶向过程中双链断裂修复的机制。
Genetics. 1999 Mar;151(3):1127-41. doi: 10.1093/genetics/151.3.1127.
引用本文的文献
1
Immunogenomic engineering of a plug-and-(dis)play hybridoma platform.免疫基因组工程的即插即用杂交瘤平台。
Nat Commun. 2016 Aug 17;7:12535. doi: 10.1038/ncomms12535.
2
Gene repeat expansion and contraction by spontaneous intrachromosomal homologous recombination in mammalian cells.哺乳动物细胞中通过自发的染色体内同源重组实现基因重复序列的扩增与收缩
Nucleic Acids Res. 2004 Feb 20;32(3):1184-96. doi: 10.1093/nar/gkh280. Print 2004.
3
Requirements for ectopic homologous recombination in mammalian somatic cells.哺乳动物体细胞中异位同源重组的要求。
Mol Cell Biol. 1996 Dec;16(12):7122-32. doi: 10.1128/MCB.16.12.7122.
4
Interchromosomal recombination is suppressed in mammalian somatic cells.
EMBO J. 1995 Aug 15;14(16):4102-7. doi: 10.1002/j.1460-2075.1995.tb00082.x.
本文引用的文献
1
A strand bias occurs in point mutations associated with variant surface glycoprotein gene conversion in Trypanosoma rhodesiense.在罗得西亚锥虫中，与变异表面糖蛋白基因转换相关的点突变存在链偏向性。
Mol Cell Biol. 1994 Jun;14(6):3971-80. doi: 10.1128/mcb.14.6.3971-3980.1994.
2
Gene conversion between unlinked sequences in the germline of mice.小鼠生殖细胞系中不连锁序列间的基因转换。
Genetics. 1994 Jul;137(3):837-43. doi: 10.1093/genetics/137.3.837.
3
A determination of the frequency of gene conversion in unmanipulated mouse sperm.对未处理的小鼠精子中基因转换频率的测定。
Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9921-5. doi: 10.1073/pnas.91.21.9921.
4
Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.人类胎儿Gγ-和Aγ-珠蛋白基因：完整的核苷酸序列表明，这些重复基因之间可发生DNA交换。
Cell. 1980 Oct;21(3):627-38. doi: 10.1016/0092-8674(80)90426-2.
5
Gene conversion: some implications for immunoglobulin genes.基因转换：对免疫球蛋白基因的一些影响。
Cell. 1981 Jun;24(3):592-4. doi: 10.1016/0092-8674(81)90082-9.
6
Sequence of the gene for the constant region of the mu chain of Balb/c mouse immunoglobulin.Balb/c小鼠免疫球蛋白μ链恒定区基因序列。
Gene. 1981 Oct;15(1):33-42. doi: 10.1016/0378-1119(81)90102-5.
7
Homologous recombination between repeated chromosomal sequences in mouse cells.小鼠细胞中重复染色体序列之间的同源重组。
Cold Spring Harb Symp Quant Biol. 1984;49:183-9. doi: 10.1101/sqb.1984.049.01.021.
8
Homologous recombination between defective neo genes in mouse 3T6 cells.小鼠3T6细胞中缺陷型新霉素基因之间的同源重组。
Cold Spring Harb Symp Quant Biol. 1984;49:171-81. doi: 10.1101/sqb.1984.049.01.020.
9
The double-strand-break repair model for recombination.用于重组的双链断裂修复模型。
Cell. 1983 May;33(1):25-35. doi: 10.1016/0092-8674(83)90331-8.
10
Deletions in immunoglobulin mu chains.免疫球蛋白μ链中的缺失
EMBO J. 1982;1(5):555-63. doi: 10.1002/j.1460-2075.1982.tb01208.x.
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