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盆腔神经切除术会阻断大鼠体内催产素促进的性接受能力。

Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats.

作者信息

Moody K M, Steinman J L, Komisaruk B R, Adler N T

机构信息

Institute of Neurological Sciences, University of Pennsylvania, Philadelphia.

出版信息

Physiol Behav. 1994 Nov;56(5):1057-60. doi: 10.1016/0031-9384(94)90343-3.

DOI:10.1016/0031-9384(94)90343-3
PMID:7824571
Abstract

The effect of bilateral pelvic, hypogastric, or pudendal neurectomy on oxytocin-induced facilitation of lordosis behavior was examined in ovariectomized, estrogen, and progesterone primed female rats. Oxytocin-induced facilitation of lordosis behavior was significantly decreased following bilateral pelvic, or combined bilateral pelvic and hypogastric neurectomy. Hypogastric only or pudendal only neurectomy had no effect on the facilitation of lordosis behavior after systemic administration of oxytocin. These results suggest that the integrity of the pelvic nerve is necessary and sufficient to mediate the stimulatory effects of systemically administered oxytocin on receptivity.

摘要

在切除卵巢并用雌激素和孕酮预处理的雌性大鼠中,研究了双侧盆腔神经、腹下神经或阴部神经切除术对催产素诱导的脊柱前凸行为促进作用的影响。双侧盆腔神经切除术或双侧盆腔神经与腹下神经联合切除术后,催产素诱导的脊柱前凸行为促进作用显著降低。单独切除腹下神经或单独切除阴部神经对全身注射催产素后脊柱前凸行为的促进作用没有影响。这些结果表明,盆腔神经的完整性对于介导全身注射催产素对接受性的刺激作用是必要且充分的。

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Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats.盆腔神经切除术会阻断大鼠体内催产素促进的性接受能力。
Physiol Behav. 1994 Nov;56(5):1057-60. doi: 10.1016/0031-9384(94)90343-3.
2
The effects of hypogastric and pelvic neurectomy on oxytocin-induced facilitation of receptivity.
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引用本文的文献

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Distinct BOLD Activation Profiles Following Central and Peripheral Oxytocin Administration in Awake Rats.清醒大鼠中枢和外周给予催产素后不同的脑区激活模式。
Front Behav Neurosci. 2015 Sep 17;9:245. doi: 10.3389/fnbeh.2015.00245. eCollection 2015.
2
Systemic oxytocin induces a prolactin secretory rhythm via the pelvic nerve in ovariectomized rats.系统性催产素通过盆腔神经在去卵巢大鼠中诱导催乳素分泌节律。
Am J Physiol Regul Integr Comp Physiol. 2011 Sep;301(3):R676-81. doi: 10.1152/ajpregu.00176.2011. Epub 2011 Jun 15.