Du Chêne de Vère F, Costantino E
Arzneimittelforschung. 1976 Apr;26(4b):740-4.
The authors refer to a previous trial with the combination 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine Sistalgin) and N-methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-aminomethanesulfonate (metamizole) (Sistalgin comp.) in patients with renoureteral lithiasis and report results obtained with the same spasmoanalgesic and a comparative preparation in patients with biliary colics. On the basis of parameters selected for the trial, the success of pramiverine/metamizole therapy in subjective and objective complaints induced by biliary stone diseases is considered positive.
作者提及了一项先前针对肾输尿管结石患者使用4,4-二苯基-N-异丙基-环己胺盐酸盐(普拉米维林西斯塔金)和N-甲基-N-(2,3-二甲基-5-氧代-1-苯基-3-吡唑啉-4-基)氨基甲磺酸盐(安乃近)(西斯塔金复方制剂)联合用药的试验,并报告了使用相同的解痉镇痛药和一种对照制剂治疗胆绞痛患者所取得的结果。基于为该试验选定的参数,普拉米维林/安乃近疗法在胆结石疾病引起的主观和客观症状方面的治疗效果被认为是积极的。