老年男性和女性的全身蛋白质周转：对两种蛋白质摄入量的反应。

Whole-body protein turnover in elderly men and women: responses to two protein intakes.

作者信息

Pannemans D L, Halliday D, Westerterp K R

机构信息

Department of Human Biology, University of Limburg, Maastricht, Netherlands.

出版信息

Am J Clin Nutr. 1995 Jan;61(1):33-8. doi: 10.1093/ajcn/61.1.33.

DOI:10.1093/ajcn/61.1.33

PMID:7825534

Abstract

In this study the effect of protein intake (12% and 21% of total energy intake, diets A and B, respectively) on nitrogen balance and on whole-body protein turnover (PT) was measured in 17 elderly men and 11 elderly women (mean +/- SD: 74 +/- 12 y and 68 +/- 9 y, respectively) with different levels of physical activity. Mean (+/- SD) nitrogen balance (diet A: -0.004 +/- 0.027 g.kg-1.d-1, diet B: 0.011 +/- 0.064 g.kg-1.d-1) did not differ significantly from zero during either diet. PT increased significantly when the protein content of the diet increased from 12% to 21% of total energy (P < 0.0001). There was a positive correlation between protein intake and PT (diet A: synthesis and breakdown, P < 0.01; diet B: synthesis, P < 0.001; breakdown, P < 0.0001). PT rates were significantly higher for men when compared with women, even when corrections were made for differences in body composition (P < 0.05).

摘要

在本研究中，对17名老年男性和11名老年女性（平均±标准差：分别为74±12岁和68±9岁）进行了不同身体活动水平下蛋白质摄入量（分别占总能量摄入的12%和21%，即饮食A和饮食B）对氮平衡和全身蛋白质周转率（PT）影响的测量。在两种饮食期间，平均（±标准差）氮平衡（饮食A：-0.004±0.027g·kg⁻¹·d⁻¹，饮食B：0.011±0.064g·kg⁻¹·d⁻¹）与零无显著差异。当饮食中蛋白质含量从总能量的12%增加到21%时，PT显著增加（P<0.0001）。蛋白质摄入量与PT之间存在正相关（饮食A：合成和分解，P<0.01；饮食B：合成，P<0.001；分解，P<0.0001）。即使对身体成分差异进行校正后，男性的PT率仍显著高于女性（P<0.05）。