Sakly A, Achour A, Zouaghi H
Ecole Supérieure des Sciences et Techniques de la Santé, Monastir, Tunisie.
Ann Urol (Paris). 1994;28(5):265-7.
We have recently suggested that vitamin A could protect against experimental lithiasis by repairing tubular membrane cells or protection against membrane damage caused by free radicals generated during experimental lithiasis. Although vitamin E treatment demonstrated no beneficial effect on stone formation, it promoted the repair mechanism by vitamin A during experimental lithiasis and by supported the hypothesis that oxalate crystals may be destructive to renal epithelium because they are large and irregular.
我们最近提出,维生素A可通过修复肾小管膜细胞或防止实验性结石形成过程中产生的自由基对膜造成的损伤,来预防实验性结石。虽然维生素E治疗对结石形成没有显示出有益效果,但它在实验性结石形成过程中促进了维生素A的修复机制,支持了草酸盐晶体可能对肾上皮具有破坏性的假说,因为它们体积大且形状不规则。