Del Prete E, Balkowski G, Scharrer E
Institute of Veterinary Physiology, University of Zurich, Switzerland.
Appetite. 1994 Aug;23(1):79-86. doi: 10.1006/appe.1994.1036.
The influence of diet composition on feeding behavior during the hyperphagia induced by about 15% loss in body weight due to restricted feeding (5 g food/day for 7 days) was investigated in adult male rats. Rats were fed either a low-fat, high-carbohydrate diet (LF diet), a medium-fat diet (MF diet) or a carbohydrate-free, high-fat diet (HF diet). The transient hyperphagia resulting from food restriction was greater in LF- and MF-rats than in HF-rats, in which a mild hypophagia was observed following the hyperphagia. Recovery of body weight was imperfect in the HF-rats in comparison to the unrestricted controls. During the hyperphagia, the meal pattern of LF- and MF-rats was mainly characterized by an increase in meal size, whereas HF-rats showed an increase in meal frequency. These observations indicate that control of food intake by body weight in LF- and MF-rats occurs mainly by modulation of the mechanisms producing meal-ending satiety, whereas in HF-rats the mechanisms eliciting meal initiation seem to be affected by body weight.
在成年雄性大鼠中，研究了饮食组成对因限食（7天内每天5克食物）导致体重减轻约15%所引发的贪食期间进食行为的影响。给大鼠喂食低脂高碳水化合物饮食（LF饮食）、中等脂肪饮食（MF饮食）或无碳水化合物高脂肪饮食（HF饮食）。食物限制导致的短暂贪食在LF和MF大鼠中比在HF大鼠中更明显，在HF大鼠中，贪食后观察到轻度食欲不振。与未受限制的对照组相比，HF大鼠的体重恢复不完全。在贪食期间，LF和MF大鼠的进食模式主要表现为每餐食量增加，而HF大鼠则表现为进食频率增加。这些观察结果表明，LF和MF大鼠中体重对食物摄入的控制主要通过调节产生餐后饱腹感的机制来实现，而在HF大鼠中，引发进食开始的机制似乎受到体重的影响。
