Takahashi Y, Uno H, Kuriyama M, Miyata H, Shimokawa K, Kawada Y
Dept. of Urology, Gifu University School of Medicine.
Gan To Kagaku Ryoho. 1995 Jan;22(1):133-6.
A 76-year-old Japanese male consulted our hospital complaining of dysphagia. He also complained of dyspnea, and a cardiovascular disorder was detected. Otolaryngological examination revealed dysphagia due to pharyngeal tumor. Further examination detected left renal cell carcinoma with multiple pulmonary metastasis, and selective angiography revealed arteriovenous fistula in the primary tumor. After resection of the pharyngeal tumor and left nephrectomy, pharyngeal tumor was pathologically confirmed as metastasis of renal cell carcinoma. Furthermore, after left nephrectomy, the cardiovascular disorder gradually improved. Thus, the cardiovascular disorder was considered to have developed based upon the arteriovenous fistulae. Pharyngeal metastasis of renal cell carcinoma is extremely rare, and the cardiovascular disorder in this case was also an extrarenal manifestation.
一名76岁的日本男性因吞咽困难前来我院就诊。他还伴有呼吸困难,经检查发现患有心血管疾病。耳鼻喉科检查显示,吞咽困难是由咽部肿瘤引起的。进一步检查发现左肾细胞癌伴多发肺转移,选择性血管造影显示原发肿瘤存在动静脉瘘。切除咽部肿瘤和左肾后,病理证实咽部肿瘤为肾细胞癌转移。此外,左肾切除术后,心血管疾病逐渐好转。因此,认为心血管疾病是由动静脉瘘引起的。肾细胞癌的咽部转移极为罕见,本例中的心血管疾病也是一种肾外表现。