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促黄体生成素释放激素抗血清对未成熟大鼠促黄体生成素释放激素诱导排卵的阻断作用。

Blockade of LH-RH induced ovulation in immature rats by LH-RH antiserum.

作者信息

Hirsch M A, Givner M L

出版信息

Can J Physiol Pharmacol. 1976 Jun;54(3):405-8. doi: 10.1139/y76-056.

DOI:10.1139/y76-056
PMID:782672
Abstract

An in vivo method for the determination of biological potency of luteinizing hormone-releasing hormone (LH-RH) antiserum is described. The procedure involves antiserum blockade of LH-RH induced ovulation in immature rats primed with pregnant mare's serum. A modified method for the induction of LH-RH antibodies in rabbits is also detailed.

摘要

本文描述了一种用于测定促黄体生成激素释放激素（LH-RH）抗血清生物学活性的体内方法。该程序包括用孕马血清预处理未成熟大鼠，然后用抗血清阻断LH-RH诱导的排卵。文中还详细介绍了一种在兔体内诱导LH-RH抗体的改良方法。

相似文献

1
Blockade of LH-RH induced ovulation in immature rats by LH-RH antiserum.促黄体生成素释放激素抗血清对未成熟大鼠促黄体生成素释放激素诱导排卵的阻断作用。
Can J Physiol Pharmacol. 1976 Jun;54(3):405-8. doi: 10.1139/y76-056.
2
Reversal of the inhibitory action of an antiserum to luteinizing hormone releasing hormone (LH-RH) by an inactive fragment of LH-RH.促黄体生成素释放激素（LH-RH）无活性片段对LH-RH抗血清抑制作用的逆转
J Endocrinol. 1977 May;73(2):393-4. doi: 10.1677/joe.0.0730393.
3
Blockade of the preovulatory surge of LH and FSH and of ovulation by anti-LH-RH serum in rats.抗促黄体生成素释放激素血清对大鼠促黄体生成素（LH）和促卵泡生成素（FSH）排卵前高峰及排卵的阻断作用。
Endocrinology. 1974 Jul;95(1):323-5. doi: 10.1210/endo-95-1-323.
4
Measurement of plasma and hypothalamic luteinizing hormon-releasing hormone in pregnant mare serum-induced ovulating immature rats.孕马血清诱导排卵的未成熟大鼠血浆和下丘脑促黄体生成激素释放激素的测定
Neuroendocrinology. 1975;17(3):274-82. doi: 10.1159/000122363.
5
Human chorionic gonadotropin and luteinizing hormone-releasing hormone reverse the blockade of ovulation in pregnant mare's serum gonadotropin-primed immature rats by the anti-androgenic drug, hydroxyflutamide.人绒毛膜促性腺激素和促黄体生成激素释放激素可逆转抗雄激素药物羟基氟他胺对孕马血清促性腺激素预处理的未成熟大鼠排卵的阻断作用。
Can J Physiol Pharmacol. 1988 Jun;66(6):783-7. doi: 10.1139/y88-124.
6
Effect of luteinizing hormone-releasing hormone antiserum on sexual behavior in the female rat.
Pharmacol Biochem Behav. 1984 Apr;20(4):527-30. doi: 10.1016/0091-3057(84)90299-5.
7
Correlation between in vivo inhibition of gonadotropin release induced by LH-RH and the blockade of ovulation by synthetic analogues of LH-RH.促黄体生成素释放激素（LH-RH）诱导的体内促性腺激素释放抑制与LH-RH合成类似物对排卵的阻断之间的相关性。
Int J Fertil. 1978;23(4):294-9.
8
Ovulation inhibition in the pregnant mare's serum gonadotropin-treated immature rat: a bioassay for luteinizing hormone-releasing hormone antagonists.
Biol Reprod. 1984 Dec;31(5):920-4. doi: 10.1095/biolreprod31.5.920.
9
Effect of administration of anti-serum to luteinizing hormone-releasing hormone on gonadal function during the estrous cycle in the hamster.给仓鼠发情周期期间注射促黄体生成素释放激素抗血清对性腺功能的影响。
Endocrinology. 1976 Feb;98(2):490-7. doi: 10.1210/endo-98-2-490.
10
Suppression of LH-RH-induced ovulation in hamsters and rats by synthetic analogues of LH-RH.促黄体生成素释放激素（LH-RH）的合成类似物对仓鼠和大鼠中LH-RH诱导排卵的抑制作用。
J Reprod Fertil. 1976 Sep;48(1):119-24. doi: 10.1530/jrf.0.0480119.

引用本文的文献

1
Immuno-histochemical localization of LH-RH during different phases of estrus cycle of rat, with reference to the preoptic and arcuate neurons, and the ependymal cells.大鼠发情周期不同阶段促黄体生成激素释放激素（LH-RH）的免疫组织化学定位，涉及视前神经元、弓状核神经元和室管膜细胞。
Cell Tissue Res. 1976 Oct 6;173(2):143-66. doi: 10.1007/BF00221371.