Danso A P, Tobani C
Department of Surgery, University of Zimbabwe.
Cent Afr J Med. 1994 Oct;40(10):281-6.
Cytogenetic investigations throw some light into the bizarre and confusing state of intersexuality and disorders of sexual differentiation. Many a time, presentation of a patient with a totally ambiguous or mixed up external genitalia, lends confusion towards the assignment of sex to the individual patient. Even more disastrous is the assignment of the wrong sex to a patient due to the fact that inadequate investigations had been performed, followed by a hasty surgical procedure based on the inadequate investigations. With cytogenetic investigations, sex assignment is made slightly easier and more sensible. These investigations should be performed in the very early stages of life. Parents and sometimes patients themselves are, therefore, as a consequence, advised in a meaningful manner, to avoid later psychological catastrophes and hazards. Cytogenetic studies are therefore a prerequisite, an advantage, and imperative in patients with ambiguous genitalia. The experiences here involving 87 patients, have demonstrated that these investigations will always help to categorise the ambiguous genitalia patient accurately.
细胞遗传学研究为两性畸形和性分化障碍这种怪异且令人困惑的状况提供了一些线索。很多时候，患者呈现出完全模糊或混淆的外生殖器，这给确定个体患者的性别带来了困惑。更糟糕的是，由于进行的检查不充分，给患者错误地分配了性别，随后基于不充分的检查匆忙进行了手术。有了细胞遗传学研究，性别分配会稍微容易一些且更合理。这些检查应在生命的早期阶段进行。因此，会以有意义的方式建议父母，有时也包括患者自己，以避免后期出现心理灾难和危害。所以，细胞遗传学研究对于生殖器模糊的患者来说是一个先决条件、一项优势且必不可少。这里涉及87例患者的经验表明，这些检查总能有助于准确地对生殖器模糊的患者进行分类。
