Luman W, Hudson N, Choudari C P, Eastwood M A, Palmer K R
Gastroenterology Unit, Western General Hospital, Edinburgh.
Gut. 1994 Nov;35(11):1665-7. doi: 10.1136/gut.35.11.1665.
A patient undergoing repeated endoscopic injection therapy for important bleeding from a duodenal ulcer developed intestinal perforation followed by extrahepatic obstructive jaundice resulting from benign biliary stricture. It is proposed that these complications were a consequence of the use of ethanolamine oleate as part of the injection regimen and caution against the use of this material is needed, particularly as current clinical trials suggest that sclerosants offer no advantage over injection therapy with dilute adrenaline alone.
一名因十二指肠溃疡大出血接受反复内镜注射治疗的患者发生了肠穿孔，随后因良性胆管狭窄出现肝外阻塞性黄疸。据推测，这些并发症是注射方案中使用油酸乙醇胺的结果，因此需要谨慎使用该物质，特别是鉴于目前的临床试验表明，硬化剂相比单独使用稀释肾上腺素进行注射治疗并无优势。
