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大量十二指肠静脉曲张出血;肝外门静脉高压的并发症:内镜治疗及文献综述

Massive duodenal variceal bleed; complication of extra hepatic portal hypertension: Endoscopic management and literature review.

作者信息

Steevens Christopher, Abdalla Maisa, Kothari Truptesh H, Kaul Vivek, Kothari Shivangi

机构信息

Christopher Steevens, Maisa Abdalla, Vivek Kaul, Shivangi Kothari, Division of Gastroenterology and Hepatology, Center for Advanced Therapeutic Endoscopy, University of Rochester Medical Center, Rochester, NY 14642, United States.

出版信息

World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):248-52. doi: 10.4292/wjgpt.v6.i4.248.

Abstract

Bleeding from duodenal varices is reported to be a catastrophic and often fatal event. Most of the cases in the literature involve patients with underlying cirrhosis. However, approximately one quarter of duodenal variceal bleeds is caused by extrahepatic portal hypertension and they represent a unique population given their lack of liver dysfunction. The authors present a case where a 61-year-old male with history of remote crush injury presented with bright red blood per rectum and was found to have bleeding from massive duodenal varices. Injection sclerotherapy with ethanolamine was performed and the patient experienced a favorable outcome with near resolution of his varices on endoscopic follow-up. The authors conclude that sclerotherapy is a reasonable first line therapy and review the literature surrounding the treatment of duodenal varices secondary to extrahepatic portal hypertension.

摘要

据报道,十二指肠静脉曲张出血是一种灾难性事件,往往会致命。文献中的大多数病例涉及患有潜在肝硬化的患者。然而,约四分之一的十二指肠静脉曲张出血是由肝外门静脉高压引起的,鉴于这些患者没有肝功能障碍,他们代表了一个独特的群体。作者介绍了一例病例,一名有陈旧性挤压伤病史的61岁男性出现便血,经检查发现是大量十二指肠静脉曲张出血。采用乙醇胺注射硬化疗法进行治疗,患者在内镜随访中静脉曲张几乎消失,取得了良好的治疗效果。作者得出结论,硬化疗法是一种合理的一线治疗方法,并对有关肝外门静脉高压继发十二指肠静脉曲张治疗的文献进行了综述。

相似文献

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Sclerotherapy in noncirrhotic portal fibrosis.非肝硬化性门脉纤维化的硬化疗法
Dig Dis Sci. 1997 Jul;42(7):1449-53. doi: 10.1023/a:1018858525312.
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本文引用的文献

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Duodenal variceal bleeding caused by chronic pancreatitis.慢性胰腺炎所致十二指肠静脉曲张出血
Gastrointest Endosc. 2012 Apr;75(4):922-3. doi: 10.1016/j.gie.2011.05.015. Epub 2011 Jul 29.

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