血红素在红系细胞蛋白质合成调控中的作用。 - Suppr

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超能文献

The role of hemin in the regulation of protein synthesis in erythroid cells.

作者信息

London I M, CLemens M J, Ranu R S, Levin D H, Cherbas L F, Ernst V

出版信息

Fed Proc. 1976 Sep;35(11):2218-22.

PMID:782923

Abstract

摘要

相似文献

The role of hemin in the regulation of protein synthesis in erythroid cells.血红素在红系细胞蛋白质合成调控中的作用。

Fed Proc. 1976 Sep;35(11):2218-22.

Isolation of two initiation factors that can partially reverse the inhibition of protein synthesis due to hemin deficiency or the hemin-controlled translational represssor in rabbit reticulocyte lysates.从兔网织红细胞裂解物中分离出两种起始因子，它们可部分逆转由于血红素缺乏或血红素控制的翻译阻遏物导致的蛋白质合成抑制。

Arch Biochem Biophys. 1977 Apr 15;180(1):121-9. doi: 10.1016/0003-9861(77)90015-7.

Regulation of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits the rate of formation of 40S.Met-tRNAf complexes directly.血红素对蛋白质合成的调控。有证据表明，血红素控制的翻译阻遏物直接抑制40S·Met-tRNAf复合物的形成速率。

J Biol Chem. 1979 Apr 10;254(7):2378-83.

Haemin protects Met-tRNAf binding activity of isolated reticulocyte ribosomes from inactivation by protein kinase.氯化血红素可保护分离的网织红细胞核糖体的甲硫氨酸起始转运核糖核酸结合活性不被蛋白激酶灭活。

Nature. 1977 Mar 10;266(5598):191-3. doi: 10.1038/266191a0.

Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin.在双链RNA存在的情况下或在无血红素的情况下，甲酰甲硫氨酰-tRNA起始珠蛋白合成的能力。

Mol Biol Rep. 1975 Mar;2(1):49-57. doi: 10.1007/BF00357297.

The molecular mechanism of hemoglobin synthesis and its regulation in the reticulocyte.网织红细胞中血红蛋白合成及其调控的分子机制。

CRC Crit Rev Biochem. 1978;5(4):261-90. doi: 10.3109/10409237809177144.

Control of globin synthesis by the haemin-controlled translational repressor in a fractionated cell-free system from rabbit reticulocytes.在来自兔网织红细胞的分级无细胞体系中，血红素控制的翻译阻遏物对珠蛋白合成的调控

Eur J Biochem. 1978 Jan 2;82(1):123-31. doi: 10.1111/j.1432-1033.1978.tb12003.x.

Translational repression in the control of globin chain initiation by hemin.血红素对珠蛋白链起始控制中的翻译抑制作用。

Ann N Y Acad Sci. 1974 Nov 29;241(0):322-33. doi: 10.1111/j.1749-6632.1974.tb21890.x.

Control of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits formation of 80 S initiation complexes from 48 S intermediate initiation complexes.血红素对蛋白质合成的调控。有证据表明，血红素调控的翻译阻遏物会抑制48S中间起始复合物形成80S起始复合物。

J Biol Chem. 1979 Apr 10;254(7):2370-7.

Mode of action of the hemin-controlled inhibitor of protein synthesis.血红素控制的蛋白质合成抑制剂的作用模式。

Proc Natl Acad Sci U S A. 1978 Jan;75(1):243-7. doi: 10.1073/pnas.75.1.243.

引用本文的文献

Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides.通过反义寡核苷酸修复哺乳动物细胞中的地中海贫血人类β-珠蛋白mRNA

Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12840-4. doi: 10.1073/pnas.93.23.12840.

Hemin-independent control of globin synthesis in Friend erythroleukemia cells induced to differentiate.在诱导分化的弗氏红白血病细胞中，珠蛋白合成的血红素非依赖性调控。

Proc Natl Acad Sci U S A. 1982 Mar;79(6):1839-43. doi: 10.1073/pnas.79.6.1839.

Activation of the heme-stabilized translational inhibitor of reticulocyte lysates by calcium ions and phospholipid.钙离子和磷脂对网织红细胞裂解液中血红素稳定化翻译抑制剂的激活作用。

Proc Natl Acad Sci U S A. 1983 Nov;80(22):6843-7. doi: 10.1073/pnas.80.22.6843.

Protein synthesis in cell-free reticulocyte lysates on multi-hour incubation.无细胞网织红细胞裂解物在数小时孵育过程中的蛋白质合成。

Appl Biochem Biotechnol. 1987 Oct;15(3):169-89. doi: 10.1007/BF02798447.

Regulation of protein synthesis in rabbit reticulocyte lysates: purification and initial characterization of the cyclic 3':5'-AMP independent protein kinase of the heme-regulated translational inhibitor.兔网织红细胞裂解物中蛋白质合成的调节：血红素调节性翻译抑制剂的环3':5'-AMP非依赖性蛋白激酶的纯化及初步表征

Proc Natl Acad Sci U S A. 1976 Dec;73(12):4349-53. doi: 10.1073/pnas.73.12.4349.

Free cytoplasmic messenger ribonucleoprotein complexes from rabbit reticulocytes.来自兔网织红细胞的游离细胞质信使核糖核蛋白复合物。

Mol Biol Rep. 1979 May 31;5(1-2):59-64. doi: 10.1007/BF00777489.

Inhibition of protein synthesis initiation by oxidized glutathione: activation of a protein kinase that phosphorylates the alpha subunit of eukaryotic initiation factor 2.氧化型谷胱甘肽对蛋白质合成起始的抑制作用：一种使真核起始因子2的α亚基磷酸化的蛋白激酶的激活。

Proc Natl Acad Sci U S A. 1978 Sep;75(9):4110-4. doi: 10.1073/pnas.75.9.4110.

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