血红素对蛋白质合成的调控。有证据表明，血红素调控的翻译阻遏物会抑制48S中间起始复合物形成80S起始复合物。 - Suppr

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超能文献

Control of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits formation of 80 S initiation complexes from 48 S intermediate initiation complexes.

作者信息

Gross M

出版信息

J Biol Chem. 1979 Apr 10;254(7):2370-7.

PMID:372180

Abstract

摘要

相似文献

Control of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits formation of 80 S initiation complexes from 48 S intermediate initiation complexes.血红素对蛋白质合成的调控。有证据表明，血红素调控的翻译阻遏物会抑制48S中间起始复合物形成80S起始复合物。

J Biol Chem. 1979 Apr 10;254(7):2370-7.

Regulation of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits the rate of formation of 40S.Met-tRNAf complexes directly.血红素对蛋白质合成的调控。有证据表明，血红素控制的翻译阻遏物直接抑制40S·Met-tRNAf复合物的形成速率。

J Biol Chem. 1979 Apr 10;254(7):2378-83.

Isolation of two initiation factors that can partially reverse the inhibition of protein synthesis due to hemin deficiency or the hemin-controlled translational represssor in rabbit reticulocyte lysates.从兔网织红细胞裂解物中分离出两种起始因子，它们可部分逆转由于血红素缺乏或血红素控制的翻译阻遏物导致的蛋白质合成抑制。

Arch Biochem Biophys. 1977 Apr 15;180(1):121-9. doi: 10.1016/0003-9861(77)90015-7.

Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin.在双链RNA存在的情况下或在无血红素的情况下，甲酰甲硫氨酰-tRNA起始珠蛋白合成的能力。

Mol Biol Rep. 1975 Mar;2(1):49-57. doi: 10.1007/BF00357297.

Functional relationships between a reticulocyte polypeptide-chain-initiation factor (IF-MP) and the translational inhibitor involved in regulation of protein synthesis by haemin.网织红细胞多肽链起始因子（IF-MP）与参与血红素调节蛋白质合成的翻译抑制剂之间的功能关系。

Eur J Biochem. 1976 Jul 1;66(2):413-22. doi: 10.1111/j.1432-1033.1976.tb10531.x.

The role of hemin in the regulation of protein synthesis in erythroid cells.血红素在红系细胞蛋白质合成调控中的作用。

Fed Proc. 1976 Sep;35(11):2218-22.

Haemin protects Met-tRNAf binding activity of isolated reticulocyte ribosomes from inactivation by protein kinase.氯化血红素可保护分离的网织红细胞核糖体的甲硫氨酸起始转运核糖核酸结合活性不被蛋白激酶灭活。

Nature. 1977 Mar 10;266(5598):191-3. doi: 10.1038/266191a0.

The high-temperature inactivation of rabbit reticulocyte lysates by a haemin-independent mechanism.兔网织红细胞裂解物通过一种不依赖血红素的机制进行高温失活。

Eur J Biochem. 1978 Mar 15;84(2):591-600. doi: 10.1111/j.1432-1033.1978.tb12202.x.

A rabbit reticulocyte model for the role of hemin-controlled repressor in hypochromic anemias.用于研究高铁血红素控制的阻遏物在低色素性贫血中作用的兔网织红细胞模型。

J Clin Invest. 1976 Mar;57(3):594-603. doi: 10.1172/JCI108315.

Partial reaction of peptide initiation inhibited by the reticulocyte hemin-controlled repressor.肽起始的部分反应受网织红细胞血红素控制阻遏物抑制。

Biochem Biophys Res Commun. 1976 Dec 6;73(3):625-31. doi: 10.1016/0006-291x(76)90856-1.

引用本文的文献

In vitro translation studies of the cytoplasmic nonpolysomal particles containing messenger RNA.对含有信使核糖核酸的细胞质非多核糖体颗粒的体外翻译研究。

Nucleic Acids Res. 1980 Apr 25;8(8):1793-804. doi: 10.1093/nar/8.8.1793.

The control of protein synthesis by hemin in rabbit reticulocytes.血红素对兔网织红细胞中蛋白质合成的调控。

Mol Cell Biochem. 1980 May 28;31(1):25-36. doi: 10.1007/BF00817888.

Early effects of dimethylnitrosamine on the initiation of protein synthesis in mouse liver.二甲基亚硝胺对小鼠肝脏蛋白质合成起始的早期影响。

Biochem J. 1981 Feb 15;194(2):469-74. doi: 10.1042/bj1940469.

Colony formation by primitive hemopoietic progenitor cells in serum-free medium.原始造血祖细胞在无血清培养基中的集落形成。

Proc Natl Acad Sci U S A. 1985 Feb;82(3):775-9. doi: 10.1073/pnas.82.3.775.

Inhibition of binding to initiation complexes of nascent reovirus mRNA by double-stranded RNA-dependent protein kinase.双链RNA依赖性蛋白激酶对新生呼肠孤病毒mRNA起始复合物结合的抑制作用。

J Virol. 1985 May;54(2):408-13. doi: 10.1128/JVI.54.2.408-413.1985.

Protein synthesis in rabbit reticulocytes: mechanism of protein synthesis inhibition by heme-regulated inhibitor.兔网织红细胞中的蛋白质合成：血红素调节抑制剂对蛋白质合成的抑制机制。

Proc Natl Acad Sci U S A. 1979 Oct;76(10):5076-9. doi: 10.1073/pnas.76.10.5076.

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