Scalzetti E M, Gagne G M
Department of Radiology, SUNY Health Science Center at Syracuse 13210.
J Nucl Med. 1995 Feb;36(2):267-9.
We set out to determine the oxygen concentration of the argon-oxygen mixture in the technegas generator where technegas-like behavior changes to pertechnegas-like behavior which allows [99mTc]pertechnetate to enter the solution.
We prepared radioaerosols analogous to technegas and pertechnegas, with oxygen concentrations between 0% and 5%. They then were examined by thin-layer chromatography using saline as a solvent to measure the amount of [99mTc]pertechnetate moving with the solvent front as a function of oxygen concentration.
The amount of mobile pertechnetate markedly increased when the radioaerosols were created in an atmosphere containing between 0.1% and 0.2% oxygen. The transition from technegas-like to pertechnegas-like behavior occurs when the oxygen-argon gas mixture contains lower concentrations of oxygen than those used in the preparation of pertechnegas.
Argon intended for the preparation of technegas should contain no more than 0.1% oxygen.
我们着手确定在技术气体发生器中氩 - 氧混合物的氧浓度，在该发生器中，类似技术气体的行为转变为类似超技术气体的行为，这使得高锝[99mTc]酸盐能够进入溶液。
我们制备了类似于技术气体和超技术气体的放射性气溶胶，其氧浓度在0%至5%之间。然后使用盐水作为溶剂通过薄层色谱法对它们进行检测，以测量作为氧浓度函数的随溶剂前沿移动的高锝[99mTc]酸盐的量。
当在含0.1%至0.2%氧气的气氛中产生放射性气溶胶时，可移动高锝酸盐的量显著增加。当氧 - 氩气体混合物中氧气浓度低于制备超技术气体所用的浓度时，就会发生从类似技术气体行为到类似超技术气体行为的转变。
用于制备技术气体的氩气中氧含量不应超过0.1%。
