Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.
作者信息
Dolle R E, Singh J, Whipple D, Osifo I K, Speier G, Graybill T L, Gregory J S, Harris A L, Helaszek C T, Miller R E
机构信息
Department of Medicinal Chemistry, Sterling Winthrop Pharmaceuticals Research Division, Collegeville, Pennsylvania 19426.
出版信息
J Med Chem. 1995 Jan 20;38(2):220-2. doi: 10.1021/jm00002a002.
PMID:7830263
Abstract
摘要
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