MacIntyre C R, Nolan T
National Centre for Epidemiology and Population Health, Canberra, ACT.
Med J Aust. 1994 Sep 5;161(5):295-9. doi: 10.5694/j.1326-5377.1994.tb127448.x.
To assess the attitudes of Victorian vaccine providers to the pertussis component of the diphtheria-tetanus-pertussis vaccine (DTP), and to examine differences between kinds of health professionals. Also, to assess vaccine providers' understanding of National Health and Medical Research Council (NHMRC) guidelines on childhood immunisation with DTP.
We conducted a postal survey of 765 randomly selected Victorian health professionals involved in childhood vaccination, including medical officers of health (MOHs), general practitioners (GPs), maternal child health nurses (MCHNs), paediatricians and environmental health officers (EHOs).
Most (83%) knew that the pertussis component was most frequently responsible for adverse effects of DTP. Thirty-four per cent of all respondents (9% MCHNs, 23% paediatricians, 24% MOHs, 34% EHOs and 39% GPs) believed that pertussis vaccine causes permanent brain damage, 34% did not, and 32% were unsure; 39% believed it causes encephalopathy. Only 9% described vaccination practices entirely in accordance with NHMRC guidelines. Up to 58% of respondents would give diphtheria-tetanus vaccine (DT) in situations when DTP was indicated, and up to 54% would give DTP when it is clearly contraindicated. There was no correlation between knowledge of the safety of DTP and vaccination practices.
Victorian vaccine providers have doubts about the safety of pertussis vaccine. There is a need to ensure the availability and clarity of immunisation guidelines for health workers, to educate them about the use of pertussis vaccine, and to ensure that this knowledge is put into practice.
评估维多利亚州疫苗接种人员对白喉-破伤风-百日咳疫苗（DTP）中百日咳成分的态度，并研究不同类型卫生专业人员之间的差异。此外，评估疫苗接种人员对国家卫生与医学研究委员会（NHMRC）关于儿童接种DTP的指南的理解。
我们对765名随机抽取的参与儿童疫苗接种的维多利亚州卫生专业人员进行了邮寄调查，这些人员包括卫生官员（MOHs）、全科医生（GPs）、母婴健康护士（MCHNs）、儿科医生和环境卫生官员（EHOs）。
大多数人（83%）知道百日咳成分是DTP不良反应最常见的原因。所有受访者中有34%（MCHNs为9%，儿科医生为23%，卫生官员为24%，环境卫生官员为34%，全科医生为39%）认为百日咳疫苗会导致永久性脑损伤，34%的人不这么认为，32%的人不确定；39%的人认为它会导致脑病。只有9%的人完全按照NHMRC指南描述疫苗接种操作。高达58%的受访者会在需要接种DTP时接种白喉-破伤风疫苗（DT），高达54%的人会在明确禁忌时接种DTP。DTP安全性知识与疫苗接种操作之间没有相关性。
维多利亚州的疫苗接种人员对百日咳疫苗的安全性存在疑虑。需要确保为卫生工作者提供免疫指南并使其清晰易懂，对他们进行百日咳疫苗使用方面的教育，并确保这些知识得到应用。
