LeMahieu R A, Ax H A, Blount J F, Carson M, Despreaux C W, Pruess D L, Scannell J P, Weiss F, Kierstead R W
J Antibiot (Tokyo). 1976 Jul;29(7):729-34.
A new antibiotic, 3-O-oleandrosyl-5-O-desosaminylerythronolide A oxime (3) was produced from erythronolide A oxime (1) by the oleandomycin-producing culture, Streptomyces antibioticus ATCC 11891. The structure of 3 was determined by degradative studies and confirmed by X-ray analysis. Compound 3 was found to be less active, but more stable to acid, then erythromycin A oxime.
