大肠杆菌中一个负责氨苄青霉素抗性的新基因座的定位
Mapping of a new genetic locus responsible for ampicillin resistance in Escherichia coli.
作者信息
Buchanan C E, Strominger J L
出版信息
J Bacteriol. 1976 Sep;127(3):1173-6. doi: 10.1128/jb.127.3.1173-1176.1976.
Abstract
The ampicillin resistance locus of three different ampicillin-resistant, temperature-sensitive Escherichia coli mutants was mapped between proC and purE and does not correspond to any of the known genes in this region. The mutant gene responsible for the temperature sensitivity and consequent morphological changes in each mutant strain was not located in the same 5-min region, even though the two mutants characteristics co-reverted at a very high frequency.
摘要
三种不同的氨苄青霉素抗性、温度敏感型大肠杆菌突变体的氨苄青霉素抗性位点被定位在proC和purE之间，且与该区域的任何已知基因均不对应。尽管两种突变体特征以非常高的频率共同回复突变，但负责每个突变菌株温度敏感性及随之而来的形态变化的突变基因并不位于同一个5分钟区域。
相似文献
1
Mapping of a new genetic locus responsible for ampicillin resistance in Escherichia coli.大肠杆菌中一个负责氨苄青霉素抗性的新基因座的定位
J Bacteriol. 1976 Sep;127(3):1173-6. doi: 10.1128/jb.127.3.1173-1176.1976.
2
Cell-surface alterations in Escherichia coli K-12 with chromosmal mutations changing ampicillin resistance.具有改变氨苄西林抗性的染色体突变的大肠杆菌K-12中的细胞表面改变
Ann N Y Acad Sci. 1971 Jun 11;182:342-57. doi: 10.1111/j.1749-6632.1971.tb30670.x.
3
Resistance of Escherichia coli to penicillins. IV. Genetic study of mutants resistant to D,L-ampicillin concentrations o 100 mu-g-ml.大肠杆菌对青霉素的耐药性。IV. 对浓度为100微克/毫升的D,L-氨苄青霉素耐药的突变体的遗传学研究
Genet Res. 1968 Oct;12(2):169-85. doi: 10.1017/s0016672300011782.
4
Mutation in Escherichia coli K-12 mediating spherelike envelopes and changes tolerance to ultraviolet irradiation and some antibiotics.大肠杆菌K-12中的突变介导球形包膜并改变对紫外线照射和某些抗生素的耐受性。
J Bacteriol. 1969 Jun;98(3):1274-7. doi: 10.1128/jb.98.3.1274-1277.1969.
5
Colicin tolerance induced by ampicillin or mutation to ampicillin resistance in a strain of Escherichia coli K-12.氨苄青霉素诱导的大肠杆菌K - 12菌株对大肠杆菌素的耐受性或对氨苄青霉素抗性的突变。
J Bacteriol. 1971 Apr;106(1):1-13. doi: 10.1128/jb.106.1.1-13.1971.
6
Escherichia coli K-12 mutants hyperproducing chromosomal beta-lactamase by gene repetitions.通过基因重复超量产生染色体β-内酰胺酶的大肠杆菌K-12突变体
J Bacteriol. 1977 Dec;132(3):912-22. doi: 10.1128/jb.132.3.912-922.1977.
7
Mutant of Escherichia coli with anomalous cell division and ability to decrease episomally and chromosomally mediated resistance to ampicillin and several other antibiotics.具有异常细胞分裂能力且能降低附加体和染色体介导的对氨苄青霉素及其他几种抗生素耐药性的大肠杆菌突变体。
J Bacteriol. 1969 Mar;97(3):1334-42. doi: 10.1128/jb.97.3.1334-1342.1969.
8
Ampicillin-resistant mutants of Escherichia coli K-12 with lipopolysaccharide alterations affecting mating ability and susceptibility to sex-specific bacteriophages.大肠杆菌K-12的耐氨苄青霉素突变体，其脂多糖改变影响交配能力和对性别特异性噬菌体的敏感性。
J Bacteriol. 1971 Aug;107(2):420-32. doi: 10.1128/jb.107.2.420-432.1971.
9
Mutations determining generalized resistance to aminoglycoside antibiotics in Escherichia coli.决定大肠杆菌对氨基糖苷类抗生素普遍耐药性的突变
Mol Gen Genet. 1978 Apr 25;161(1):89-98. doi: 10.1007/BF00266619.
10
Resistance of Escherichia coli to penicillins. 8. Physiology of a class II ampicillin-resistant mutant.大肠杆菌对青霉素的耐药性。8. 二类氨苄西林耐药突变体的生理学特性
J Bacteriol. 1970 Mar;101(3):659-68. doi: 10.1128/jb.101.3.659-668.1970.
本文引用的文献
1
Transduction of linked genetic characters of the host by bacteriophage P1.噬菌体P1对宿主连锁遗传性状的转导
Virology. 1955 Jul;1(2):190-206. doi: 10.1016/0042-6822(55)90016-7.
2
A model for three-point analysis of random general transduction.随机普遍转导的三点分析模型
Genetics. 1966 Aug;54(2):405-10. doi: 10.1093/genetics/54.2.405.
3
Penicillin-resistant temperature-sensitive mutants of Escherichia coli which synthesize hypo- or hyper-cross-linked peptidoglycan.合成低交联或高交联肽聚糖的大肠杆菌青霉素抗性温度敏感突变体。
J Bacteriol. 1974 Feb;117(2):568-77. doi: 10.1128/jb.117.2.568-577.1974.
4
Rapid mapping of conditional and auxotrophic mutations in Escherichia coli K-12.大肠杆菌K-12中条件性突变和营养缺陷型突变的快速定位
J Bacteriol. 1973 Feb;113(2):798-812. doi: 10.1128/jb.113.2.798-812.1973.
5
Mutants of Escherichia coli with temperature-sensitive lesions in membrane phospholipid synthesis: genetic analysis of glycerol-3-phosphate acyltransferase mutants.膜磷脂合成中具有温度敏感损伤的大肠杆菌突变体：甘油-3-磷酸酰基转移酶突变体的遗传分析
Mol Gen Genet. 1972;116(3):199-210. doi: 10.1007/BF00269765.
6
Recalibrated linkage map of Escherichia coli K-12.大肠杆菌K-12的重新校准连锁图谱。
Bacteriol Rev. 1976 Mar;40(1):116-67. doi: 10.1128/br.40.1.116-167.1976.
Zotero 插件