Bramley A J
J Dairy Res. 1976 Jun;43(2):205-11. doi: 10.1017/s0022029900015752.
Small numbers of Escherichia coli were infused into both lactating and non-lactating udders. Twelve of the 17 lactating quarters infused became infected, and all 12 showed clinical symptoms of udder disease. The 5 lactating quarters which did not become infected all had pre-infusion somatic cell counts greater than 300000 cells/ml milk, whilst all the quarters which became infected had cell counts less than 300000 cells/ml milk. E. coli was subsequently recovered from only 6 of the 16 non-lactating quarters infused. In only 2 of these quarters did clinical infection follow, both quarters being in a cow infused 2 d before calving. The remaining 4 quarters from which E. coli was recovered were all negative within 5 d of infusion. These differences in susceptibility are discussed, particularly with reference to the frequent occurrence of coliform mastitis at and shortly after calving.
将少量大肠杆菌注入泌乳和非泌乳的乳房。注入的17个泌乳乳腺中有12个受到感染，且所有12个都表现出乳房疾病的临床症状。未受感染的5个泌乳乳腺在注入前体细胞计数均大于300000个/毫升牛奶，而所有受感染的乳腺细胞计数均小于300000个/毫升牛奶。随后，在注入的16个非泌乳乳腺中，仅从6个中分离出大肠杆菌。其中只有2个乳腺发生了临床感染，这两个乳腺均来自一头在产犊前2天注入大肠杆菌的奶牛。从其体内分离出大肠杆菌的其余4个乳腺在注入后5天内均呈阴性。文中讨论了这些易感性差异，特别是参照产犊时及产犊后不久大肠埃希菌性乳腺炎的频繁发生情况进行了讨论。
