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口服氯胺酮成功治疗带状疱疹后神经痛。

Successful treatment of postherpetic neuralgia with oral ketamine.

作者信息

Hoffmann V, Coppejans H, Vercauteren M, Adriaensen H

机构信息

Department of Anesthesia, University Hospital of Antwerpen, Edegem, Belgium.

出版信息

Clin J Pain. 1994 Sep;10(3):240-2. doi: 10.1097/00002508-199409000-00011.

DOI:10.1097/00002508-199409000-00011
PMID:7833583
Abstract

OBJECTIVE

To demonstrate the possibilities of the use of oral ketamine in the treatment of postherpetic neuralgia.

SETTING

A pain clinic in a university hospital.

PATIENT

A patient with postherpetic neuralgia of the ophthalmic nerve.

INTERVENTION

Subcutaneous and later oral ketamine after classical treatment had failed.

RESULTS

A complete recovery was accomplished without any sign of side effects.

CONCLUSIONS

Oral ketamine may provide an alternative in the treatment of postherpetic neuralgia. The possible mechanism of action by its N-methyl-D-aspartate (NMDA) blocking properties is discussed.

摘要

目的

证明口服氯胺酮用于治疗带状疱疹后神经痛的可能性。

背景

大学医院的疼痛诊所。

患者

一名患有眼神经带状疱疹后神经痛的患者。

干预措施

在传统治疗失败后,先采用皮下注射氯胺酮,随后口服氯胺酮。

结果

实现了完全康复,且无任何副作用迹象。

结论

口服氯胺酮可能为带状疱疹后神经痛的治疗提供一种替代方法。讨论了其通过N-甲基-D-天冬氨酸(NMDA)阻断特性可能的作用机制。

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