Red cell acid phosphatase types and GC polymorphisms in Mérida, Oaxaca, León, and Saltillo, Mexico.

Red cell acid phosphatase types and GC polymorphisms were studied in Mérida and Oaxaca, Mexico. GC polymorphisms were also investigated in León and Saltillo. The ACPA, ACPB, and ACPC gene frequencies were 0.215, 0.770, and 0.015 respectively, in Mérida and 0.205, 0.788, and 0.002, respectively, in Oaxaca. In Oaxaca the ACPR gene had a frequency of 0.005. The results are similar to other Mestizo groups studied in Mexico; it is concluded that the ACPC and ACPR genes were introduced by admixture of native Amerindians with whites and blacks, respectively. The GC1S, GC1F, and GC*2 gene frequencies were 0.489, 0.289 and 0.222, respectively, in León; 0.500, 0.272, and 0.228, respectively, in Mérida; 0.454, 0.337, and 0.209, respectively, in Oaxaca; and 0.505, 0.356, and 0.139, respectively, in Saltillo. These results are similar to what has been obtained in other Mestizo populations and Indian groups in Mexico, probably because the main ethnic component in both is Amerindian.