慢性肾性镁消耗所致低镁血症患者的红细胞和单核血细胞镁浓度正常。
Erythrocyte and mononuclear blood cell magnesium concentrations are normal in hypomagnesemic patients with chronic renal magnesium wasting.
作者信息
Elin R J, Hosseini J M, Gill J R
机构信息
Clinical Pathology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892.
出版信息
J Am Coll Nutr. 1994 Oct;13(5):463-6. doi: 10.1080/07315724.1994.10718435.
OBJECTIVE
The purpose of this study was to determine the plasma, erythrocyte, and mononuclear blood cell (MBC) magnesium concentrations in patients with chronic, severe hypomagnesemia due to a chronic magnesium-wasting tubulopathy.
METHODOLOGY
Six patients with Bartter's syndrome and five patients with magnesium-wasting tubulopathy were compared with normal subjects. We determined magnesium in plasma, erythrocytes, and MBCs.
RESULTS
Patients with chronic magnesium-wasting tubulopathy had a significantly lower plasma magnesium concentration than controls, but erythrocyte magnesium concentration and MBC magnesium concentration and content did not differ significantly between patients and controls.
CONCLUSION
Two disorders with chronic magnesium-wasting tubulopathies are associated with a low plasma magnesium concentration but normal erythrocyte and MBC magnesium.
目的
本研究旨在测定因慢性镁消耗性肾小管病导致的慢性、重度低镁血症患者的血浆、红细胞及单核血细胞（MBC）镁浓度。
方法
将6例巴特综合征患者和5例镁消耗性肾小管病患者与正常受试者进行比较。我们测定了血浆、红细胞及MBC中的镁含量。
结果
慢性镁消耗性肾小管病患者的血浆镁浓度显著低于对照组，但患者与对照组之间的红细胞镁浓度、MBC镁浓度及含量无显著差异。
结论
两种慢性镁消耗性肾小管病均与血浆镁浓度降低但红细胞和MBC镁正常有关。
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