DNA marker D11S384 shows zero recombination with the ataxia-telangiectasia locus in North American families.
作者信息
Lench N J, Athma P, Ottaiano A, Sribney W M, Highsmith E, Swift M
机构信息
Division of Human Molecular Genetics, New York Medical College, Valhalla.
出版信息
Int J Radiat Biol. 1994 Dec;66(6 Suppl):S67-9.
PMID:7836855
Abstract
At the genetic locus D11S384, one probe detects a Taql RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.
摘要
Zotero 插件