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高压氧疗法治疗颈部坏死性筋膜炎

Treatment of cervical necrotizing fasciitis with hyperbaric oxygen therapy.

作者信息

Langford F P, Moon R E, Stolp B W, Scher R L

机构信息

Division of Otolaryngology-Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710.

出版信息

Otolaryngol Head Neck Surg. 1995 Feb;112(2):274-8. doi: 10.1016/S0194-59989570250-4.

Abstract

Hyperbaric oxygen therapy has significantly improved the management of necrotizing fasciitis of the extremities and trunk. Its role in cervical necrotizing fasciitis has not been fully evaluated. Historically, necrotizing fasciitis has been associated with considerable morbidity and mortality. This report discusses our experience with cervical necrotizing fasciitis in six patients treated from 1986 to 1993 who received hyperbaric oxygen therapy. All patients survived. In all cases infection was of probable odontogenic origin. Most patients in whom necrotizing fasciitis develops have identifiable risk factors; however, two patients in this series were previously healthy, and there was no relationship between hospital course and identified risk factors. Clinical presentation and microbiology are reviewed together with the rationale for hyperbaric oxygen therapy as an adjunct to broad-spectrum antibiotics and aggressive early surgical debridement.

摘要

高压氧疗法显著改善了四肢和躯干坏死性筋膜炎的治疗效果。其在颈部坏死性筋膜炎中的作用尚未得到充分评估。从历史上看,坏死性筋膜炎一直与相当高的发病率和死亡率相关。本报告讨论了我们在1986年至1993年期间治疗的6例接受高压氧疗法的颈部坏死性筋膜炎患者的经验。所有患者均存活。所有病例感染可能源于牙源性。大多数发生坏死性筋膜炎的患者都有可识别的危险因素;然而,该系列中的两名患者此前身体健康,且病程与已识别的危险因素之间没有关联。本文将临床表现、微生物学与高压氧疗法作为广谱抗生素和积极早期手术清创辅助手段的基本原理一同进行了综述。

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