氮杂蒽醌和二氮杂蒽醌衍生物的合成及其体外细胞毒性活性
Synthesis and in vitro cytotoxic activity of aza- and diazaanthraquinone derivatives.
作者信息
Nebois P, do Nascimento S C, Boitard M, Bartoli M H, Fillion H
机构信息
Laboratoire de Chimie Organique, Institut des Sciences Pharmaceutiques et Biologiques, Lyon, France.
出版信息
Pharmazie. 1994 Nov;49(11):819-21.
PMID:7838868
Abstract
Some 1,4-dihydro aza- and 1,4-dihydro diazaanthraquinone derivatives have been synthesized and submitted to in vitro cytotoxicity tests towards L 1210, MDA-MB 231 and PC3 cell lines. Some of the new substances showed significant activity.
摘要
已经合成了一些1,4 - 二氢氮杂和1,4 - 二氢二氮杂蒽醌衍生物，并对L 1210、MDA - MB 231和PC3细胞系进行了体外细胞毒性测试。一些新物质表现出显著活性。
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