Richter W, Lee S, Warren W S, He Q
Department of Chemistry, Princeton University, NJ 08544.
Science. 1995 Feb 3;267(5198):654-7. doi: 10.1126/science.7839140.
A magnetic resonance imaging technique based on intermolecular multiple-quantum coherences in solution (the correlated spectroscopy revamped by asymmetric z gradient echo detection or CRAZED experiment) is described here. Correlations between spins in different molecules were detected by magnetic-field gradient pulses. In order for a correlation to yield an observable signal, the separation between the two spins must be within a narrow band that depends on the area of the gradient pulses. The separation can be tuned from less than 10 micrometers to more than 1 millimeter, a convenient range for many applications.
本文描述了一种基于溶液中分子间多量子相干性的磁共振成像技术（通过不对称z梯度回波检测改进的相关光谱法或CRAZED实验）。通过磁场梯度脉冲检测不同分子中自旋之间的相关性。为了使相关性产生可观测信号，两个自旋之间的间距必须在一个窄带内，该窄带取决于梯度脉冲的面积。该间距可从小于10微米调整到大于1毫米，这对许多应用来说是一个方便的范围。
