[肌萎缩侧索硬化症患者人体骨骼肌成分的变化]
[Change in the composition of human skeletal muscles in amyotrophic lateral sclerosis].
作者信息
Kovalev L I, Khdaĭdatov A I, Galiuk M A, Shishkin S S, Niiazbekova A S, Gelashvili I N, Zavalishin I A
出版信息
Vopr Med Khim. 1994 Sep-Oct;40(5):42-5.
PMID:7839670
Abstract
Protein composition of human skeletal muscle impaired with lateral amyotropic sclerosis was studied by means of two-dimensional electrophoresis. Some protein fractions were altered. Characteristic property of all the preparations studied proved to be disappearance of three protein fractions of 35 kDa molecular mass and with pI 5.9, 6.0 and 6.1.
摘要
采用二维电泳法研究了侧索肌萎缩硬化症患者受损的人体骨骼肌的蛋白质组成。一些蛋白质组分发生了改变。所研究的所有制剂的特征特性是分子量为35 kDa、等电点为5.9、6.0和6.1的三种蛋白质组分消失。
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