De Reuck J, De la Meilleure G, Boon P, Decoo D, Strijckmans K, Goethals P, Lemahieu I
Department of Neurology, University Hospital, University of Ghent, Belgium.
Acta Neurol Belg. 1994;94(4):239-44.
The cerebral haemodynamic and metabolic changes due to cavernous angiomas in three patients and to arteriovenous malformations in four patients were compared by positron emission tomography, using the steady state technique with 15O. In the brains with a cavernous angioma no important changes in blood flow were observed. Only a decreased oxygen consumption was present in the cortex supplied by the arterial branches of the angioma, most probably related to neuronal deafferentation. In the four cases of arteriovenous malformation cerebral blood flow was significantly increased in the territory of the feeding vessels of the angioma. In the two huge ones the oxygen extraction rate was increased in the other vascular areas remote from the supply territory of the angioma, indicating chronic ischaemia. The present study confirms that chronic vascular steal phenomena can occur in large arteriovenous malformations, while cavernous angiomas do not induce important haemodynamic changes.
通过使用含(^{15}O)的稳态技术的正电子发射断层扫描，比较了3例海绵状血管瘤患者和4例动静脉畸形患者脑部的血流动力学和代谢变化。在患有海绵状血管瘤的大脑中，未观察到血流的重要变化。仅在血管瘤动脉分支供应的皮质中存在氧消耗降低，这很可能与神经元去传入有关。在4例动静脉畸形病例中，血管瘤供血血管区域的脑血流量显著增加。在两个巨大的动静脉畸形中，远离血管瘤供血区域的其他血管区域的氧摄取率增加，表明存在慢性缺血。本研究证实，大型动静脉畸形可发生慢性血管盗血现象，而海绵状血管瘤不会引起重要的血流动力学变化。
