Vanpaemel L, Helders P J, Kuis W, Pruijs H, Huber J, Keessen W
Department of Pediatric Orthopedics, University Hospital for Children and Youth, Het Wilhelmina Kinderziekenhuis, Utrecht, The Netherlands.
Acta Orthop Scand. 1994 Dec;65(6):585-8. doi: 10.3109/17453679408994609.
2 boys had unilateral Perthes' disease at the age of 5 years. After 6 and 7 years, respectively, both patients developed contralateral femoral head necrosis with rapid destruction leading to ankylosis of the hip. Histology of the synovium showed nonspecific synovitis. Both patients fulfilled criteria for oligo-articular juvenile chronic arthritis (JCA). The association with Perthes' disease suggests a common etiology.