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[400例冠状动脉成形术患者的长期随访]

[The long-term follow-up of 400 coronary angioplasty patients].

作者信息

Frade García J, Mata L A, Mendoza Gómez R, Carrillo Anaya A

机构信息

Servicio de Hemodinamia, Hospital Español, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1994 Sep-Oct;64(5):461-7.

PMID:7840729
Abstract

From October 1985 to May 1992, 400 patients had coronary angioplasty of 518 stenotic lesions with a 92% success rate. Mean stenosis was reduced from 88 to 15%. We had 25 major complications (6%): 8 emergency bypass surgery (2%), MI in 12 pts (3%) and 5 deaths (1%). Follow-up was possible in 329 of the 367 patients with a successful procedure (90%), with a mean follow-up of 44 months. We performed coronary angiogram in 113 patients with clinical data suggestive of restenosis, restenosis was found in 73, progression of the coronary atherosclerosis in 18 and 22 (19%) had no evidence of restenosis. A second coronary angioplasty was performed in 44 pts with a 93% success rate, 22 were sent to coronary bypass surgery and medical treatment was given to 7 patients. The 18 pts with progression of the disease were also sent to bypass surgery. During follow-up 25% of the patients required a second angioplasty or bypass surgery. A total of 115 (35%) pts showed evidence of restenosis: in 73 pts (22%) a coronary angiogram revealed restenosis, 12 had angina, 15 myocardial infarction and 15 died of cardiovascular disease. At the end of follow-up 259 pts (79%) were free of myocardial infarction, bypass surgery or cardiovascular death. Survival rate at 3.7 years was 94.5%. In conclusion, coronary angioplasty showed to be safe, effective and with a good long term outcome.

摘要

1985年10月至1992年5月,400例患者接受了冠状动脉成形术,治疗518处狭窄病变,成功率为92%。平均狭窄率从88%降至15%。我们有25例主要并发症(6%):8例急诊搭桥手术(2%),12例患者发生心肌梗死(3%),5例死亡(1%)。367例手术成功的患者中有329例(90%)获得随访,平均随访时间为44个月。我们对113例有再狭窄临床迹象的患者进行了冠状动脉造影,发现73例有再狭窄,18例冠状动脉粥样硬化进展,22例(19%)无再狭窄证据。44例患者接受了第二次冠状动脉成形术,成功率为93%,22例被送去进行冠状动脉搭桥手术,7例接受药物治疗。18例病情进展的患者也被送去进行搭桥手术。随访期间,25%的患者需要进行第二次成形术或搭桥手术。共有115例(35%)患者有再狭窄证据:73例(22%)冠状动脉造影显示有再狭窄,12例有心绞痛,15例有心肌梗死,15例死于心血管疾病。随访结束时,259例(79%)患者无心肌梗死、搭桥手术或心血管死亡。3.7年的生存率为94.5%。总之,冠状动脉成形术显示出安全、有效且长期预后良好。

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