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人眼黄斑和脉络膜血管系统中重力诱导的稳态反应。

Gravity-induced homeostatic reactions in the macular and choroidal vasculature of the human eye.

作者信息

Lovasik J V, Kergoat H

机构信息

University of Montreal, School of Optometry, Quebec, Canada.

出版信息

Aviat Space Environ Med. 1994 Nov;65(11):1010-4.

PMID:7840740
Abstract

We quantified the changes in macular and choroidal blood flow during body inversion to elaborate their hemodynamic attributes and relate them to our previously reported effects of inversion on visual neural function. Ten healthy subjects took part in the study. The intraocular pressure (IOP) was altered through graded body tilts. Macular and choroidal pulsatile ocular blood flow (POBF) were measured with an Oculix BFS 2000 and a Langham OBF system, respectively. Body inversion caused a systematic decrease in the POBF for all subjects. Systematic changes in macular leukocyte velocity and density were also found with inversion. Six of ten subjects showed a reciprocal relationship between the leukocyte density and velocity as a function of body orientation, while parallel changes in the leukocyte density and velocity were seen during inversion for the remaining subjects. Our results may reflect individual strategies for autoregulation within the macular circulation and an absence of autoregulation in the pulsatile component of the choroidal circulation.

摘要

我们对身体倒置过程中黄斑和脉络膜血流的变化进行了量化,以阐明它们的血流动力学特性,并将其与我们之前报道的倒置对视觉神经功能的影响联系起来。十名健康受试者参与了这项研究。通过分级身体倾斜来改变眼压。分别使用Oculix BFS 2000和Langham OBF系统测量黄斑和脉络膜搏动性眼血流(POBF)。身体倒置导致所有受试者的POBF系统性下降。倒置时还发现黄斑白细胞速度和密度有系统性变化。十名受试者中有六名表现出白细胞密度和速度之间随身体方位变化的相互关系,而其余受试者在倒置过程中白细胞密度和速度则呈现平行变化。我们的结果可能反映了黄斑循环中个体的自动调节策略以及脉络膜循环搏动成分中缺乏自动调节。

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