Gislason H, Svanes K
Surgical Research Laboratory, University of Bergen, Norway.
J Physiol Pharmacol. 1994 Sep;45(3):369-76.
Superficial mucosal damage caused by a mild irritant (2 M NaCl) results in release of histamine and probably prostaglandins giving increased GMBF. This hyperemic response contributes to protect the mucosa during the early phase of repair after damage by supplying the mucosa with bicarbonate and by eliminating back diffusing acid and other toxic substances such as ethanol. We conclude that histamine plays an important role in the blood flow regulation in the stomach.
由轻度刺激物（2M氯化钠）引起的浅表黏膜损伤会导致组胺以及可能的前列腺素释放，从而使胃黏膜血流量增加。这种充血反应通过为黏膜提供碳酸氢盐、消除反流的酸和其他有毒物质（如乙醇），在损伤后的修复早期阶段有助于保护黏膜。我们得出结论，组胺在胃的血流调节中起重要作用。
