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不完全川崎病的发病率及临床特征

Incidence and clinical features of incomplete Kawasaki disease.

作者信息

Fukushige J, Takahashi N, Ueda Y, Ueda K

机构信息

Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Acta Paediatr. 1994 Oct;83(10):1057-60. doi: 10.1111/j.1651-2227.1994.tb12985.x.

DOI:10.1111/j.1651-2227.1994.tb12985.x
PMID:7841704
Abstract

During the nine-year period from 1983 to 1991, a total of 242 patients (142 males and 100 females) presenting with Kawasaki disease were seen at one hospital. Among them, 25 (10%) patients demonstrated incomplete Kawasaki disease and 17 of these 25 (68%) lacked two of the six principal symptoms of Kawasaki disease, with the most frequently missing symptoms being cervical lymphadenopathy and polymorphous exanthema. The typical laboratory features of Kawasaki disease, such as elevated erythrocyte sedimentation rate, leukocytosis, anemia, positive C-reactive protein and thrombocytosis were also seen in the incomplete cases. None of the 25 patients underwent iv gamma-globulin therapy while in 1 (4%), transient dilatation of the coronary artery was recognized. Incomplete Kawasaki disease may therefore be characterized by a less frequent association of rash, cervical lymphadenopathy and coronary involvement.

摘要

在1983年至1991年的九年期间,一家医院共收治了242例川崎病患者(男性142例,女性100例)。其中,25例(10%)患者表现为不完全川崎病,这25例中的17例(68%)缺乏川崎病六个主要症状中的两个,最常缺失的症状是颈部淋巴结肿大和多形性皮疹。不完全病例也出现了川崎病的典型实验室特征,如红细胞沉降率升高、白细胞增多、贫血、C反应蛋白阳性和血小板增多。25例患者均未接受静脉注射丙种球蛋白治疗,而有1例(4%)出现冠状动脉短暂扩张。因此,不完全川崎病的特征可能是皮疹、颈部淋巴结肿大和冠状动脉受累的发生率较低。

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