Liu D S, Chen K Z, Zhang C L
Affiliated Hospital of Shandong Medical University, Jinan.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Aug;14(8):454-7.
The relationship between brain function and syndrome-types of TCM in 51 patients with non-insulin dependent diabetes mellitus (NIDDM) was observed. The syndromes were divided into three types. (1) Yin Deficiency with internal excessive Heat (YDIEH), 15 cases; (2) Qi-Yin Deficiency (QYD), 21 cases; (3) Deficiency of both Yin and Yang (DYY), 15 cases. The control group consisted of 30 healthy subjects matched in age, sex and educational level. The brain function were tested by neurobehavioral and neuroelectrophysiological tests. The former included short-term memory, thinking, eye-hand coordination and emotion tests; the latter consisted of brainstem auditory evoked potentials (BAEP), visual evoked potentials (VEP) and somatosensory evoked potentials (SEP). The results showed that the brain function in YDIEH group approached normal controls, and the brain function in QYD and QYY groups were significantly deteriorated. The results suggested that the brain function were correlated with the syndrome-types of patients with NIDDM. This would be valuable for diagnosis and treatment of NIDDM in TCM.
观察了51例非胰岛素依赖型糖尿病(NIDDM)患者的脑功能与中医证型的关系。证型分为三种。(1)阴虚内热(YDIEH),15例;(2)气阴两虚(QYD),21例;(3)阴阳两虚(DYY),15例。对照组由30名年龄、性别和教育水平相匹配的健康受试者组成。通过神经行为和神经电生理测试来检测脑功能。前者包括短期记忆、思维、眼手协调和情绪测试;后者包括脑干听觉诱发电位(BAEP)、视觉诱发电位(VEP)和体感诱发电位(SEP)。结果显示,YDIEH组的脑功能接近正常对照组,而QYD组和DYY组的脑功能明显恶化。结果提示,脑功能与NIDDM患者的证型相关。这对中医诊断和治疗NIDDM具有重要价值。